| Effect of date seeds on oxidative damage and antioxidant status in vivo. | |
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MedLine Citation:
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PMID: 21480263 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Date seeds have been shown to contain high amounts of antioxidants. However, in vivo studies on date seeds are lacking. Therefore the purpose of this study was to determine the effect of date seeds on oxidative damage and antioxidant status in vivo. Male Wistar rats were fed a basal diet containing 0, 70 or 140 g kg(-1) date seeds for 30 days. All three diets were isonitrogenous and isocaloric. Indication of oxidative damage was assessed in the liver and serum, and antioxidant status was assessed in the liver. Serum biochemical parameters, including indicators of tissue cellular damage and complete blood count with differential, were also determined. RESULTS: The results showed that date seeds significantly (P < 0.05) reduced liver and serum malondialdehyde (a lipid peroxidative damage product) and serum lactate dehydrogenase and creatine kinase. Liver antioxidants (vitamin E, vitamin C, glutathione, superoxide dismutase, glutathione peroxidase and catalase), complete blood count with differential and other serum biochemical parameters assessed were not significantly altered by date seeds. CONCLUSION: The results obtained suggest a protective effect of date seeds against in vivo oxidative damage, possibly through the action of their bioactive antioxidants. Copyright © 2011 Society of Chemical Industry. |
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Authors:
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Hosam M Habib; Wissam H Ibrahim |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-7 |
Journal Detail:
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Title: Journal of the science of food and agriculture Volume: - ISSN: 1097-0010 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376334 Medline TA: J Sci Food Agric Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Society of Chemical Industry. |
Affiliation:
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Department of Nutrition and Health, Faculty of Food and Agriculture, United Arab Emirates University, PO Box 17555, Al Ain, UAE. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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