Document Detail

Effect of dantrolene sodium on the spastic external urethral sphincter recorded by sphincterometry.
MedLine Citation:
PMID:  642098     Owner:  NLM     Status:  MEDLINE    
An improved method of sphincterometry is described, which is easy to perform in men and also may be used in women. It gives reproducible results in the individual patient. The maximum pressure was found by radiographic and reflexological examinations of the external urethral sphincter. When 0.5 mg./kg. body weight dantrolene sodium was injected intravenously the resistance of the external urethral sphincter was found to be reduced significantly, presumably reflecting a reduction of reflex activity.
E Pedersen; H Harving; B Klemar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  119     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-06-12     Completed Date:  1978-06-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  403-5     Citation Subset:  AIM; IM    
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MeSH Terms
Dantrolene / pharmacology*
Hydantoins / pharmacology*
Muscle Spasticity / physiopathology
Muscles / drug effects*,  physiopathology
Paraplegia / physiopathology
Urethra / drug effects*,  physiopathology
Urinary Bladder, Neurogenic / physiopathology
Reg. No./Substance:
0/Hydantoins; 7261-97-4/Dantrolene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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