Document Detail


Effect of controlled ovarian hyperstimulation treatment on cardiac function.
MedLine Citation:
PMID:  21291037     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the effects of controlled ovarian hyperstimulation (COH) treatment on cardiac functions using tissue Doppler imaging (TDI).
STUDY DESIGN: Twenty-one patients aged 22-35 years were enrolled to COH cycles. Each subject underwent a conventional transthoracic echocardiographic examination that included an assessment of cardiac function. Measurements were taken twice--the first on the second day of the cycle and the second on the day when human chorionic gonadotropin was administered. Twenty-one healthy women were chosen for the control group.
RESULTS: The COH treatment did not cause favorable cardiac function changes. The parameters showing the left ventricular diastolic function such as early diastolic peak flow velocity (E), late diastolic peak flow velocity (A), mitral E/A ratios, mitral E wave, deceleration time (DT), lateral isovolumic relaxation time (IVRT), and left ventricular myocardial performance index (LVMPI) were not changed. The COH treatment did not affect the right ventricular diastolic functions such as tricuspid valve E wave, DT, right ventricular (RV) IVRT, or right ventricular myocardial performance index (RVMPI). Concurrently, the COH treatment showed no effects on the right and left ventricular systolic functions.
CONCLUSION: TDI findings reveal no effects of the COH treatment on cardiac function.
Authors:
Ayla Uckuyu; Ceylan F Ciftci; Emel E Ozcimen; Ozgur Ciftci; Erzat Toprak; Erdem Turhan
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  55     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2011-02-04     Completed Date:  2011-06-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  503-8     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Faculty of Medicine, Baskent University, Konya, Turkey. uckuyuayla@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Pressure / drug effects
Female
Follicle Stimulating Hormone, Human / pharmacology*
Gonadotropin-Releasing Hormone / analogs & derivatives*,  pharmacology
Heart Rate / drug effects
Hormone Antagonists / pharmacology*
Humans
Ovulation Induction*
Stroke Volume / drug effects
Ventricular Function, Left / drug effects*
Ventricular Function, Right / drug effects*
Young Adult
Chemical
Reg. No./Substance:
0/Follicle Stimulating Hormone, Human; 0/Hormone Antagonists; 33515-09-2/Gonadotropin-Releasing Hormone; OON1HFZ4BA/cetrorelix

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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