| Effect of contralateral pure tone stimulation on distortion emissions suggests a frequency specific functioning of the efferent cochlear control. | |
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MedLine Citation:
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PMID: 22262828 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Contralateral acoustic stimulation (CAS) with white noise and pure tone stimuli was used to assess frequency specificity of efferent olivocochlear control of cochlear mechanics in the gerbil. Changes of the cochlear amplifier can be monitored by distortion product otoacoustic emissions (DPOAEs) which are a byproduct of the nonlinear amplification by the outer hair cells. We used the quadratic DPOAE f2-f1 as ipsilateral probe as it is known to be sensitive to efferent olivocochlear activity. White noise CAS, used to evoke efferent activity, had maximal effects on the DPOAE level for f2-stimulus frequencies of 5-7 kHz. The dominant effect during CAS was a DPOAE level increase of up to 13.5 dB. The frequency specificity of the olivocochlear system was evaluated by presenting pure tones (0.5-38 kHz) as contralateral stimuli in order to evoke efferent activity. Maximal DPOAE level changes were triggered by CAS frequencies close to the frequency of the DPOAE elicitor tones (tested f2 range: 2.5-15 kHz). The effective CAS frequency range covered 1.4-2.4 octaves and was centered 0.42 octaves below the DPOAE elicitor tone f2. The frequency-specific effect of CAS with pure tones suggests a dedicated central control of mechanical adjustments for peripheral frequency processing. |
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Authors:
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Heike Althen; Anna Wittekindt; Bernhard Gaese; Manfred Kössl; Cornelius Abel |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-18 |
Journal Detail:
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Title: Journal of neurophysiology Volume: - ISSN: 1522-1598 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375404 Medline TA: J Neurophysiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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1nstitut für Zellbiologie und Neurowissenschaft, Goethe-Universität, Frankfurt/Main, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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