Document Detail


Effect of continuous jejunal perfusion of elemental and complex nutritional solutions on pancreatic enzyme secretion in human subjects.
MedLine Citation:
PMID:  631640     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pancreatic secretion of lipase and chymotrypsin in response to elemental diets and a crushed food homogenate was studied in normal subjects. The solutions were infused at constant flow rates at the ligament of Treitz with polyethylene glycol as a nonabsorbable marker. A triple lumen tube was used, enabling collection of secretions at 35 and 70 cm from the infusion point. The results show that a crushed food homogenate has a greater stimulative effect on pancreatic enzyme secretion than the elemental solutions and that this can be directly related to its greater nitrogen content. The osmolality of the infused solutions does not appear to be important. The relative merits of the solutions tested and total parental nutrition in reducing pancreatic enzyme secretion are discussed.
Authors:
N Vison; P Hecketsweiler; J Butel; J J Bernier
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gut     Volume:  19     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-05-08     Completed Date:  1978-05-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  194-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Chymotrypsin / secretion*
Diet*
Energy Intake
Humans
Jejunum / physiology*
Lipase / secretion*
Nitrogen / administration & dosage
Pancreas / secretion*
Perfusion
Chemical
Reg. No./Substance:
7727-37-9/Nitrogen; EC 3.1.1.3/Lipase; EC 3.4.21.1/Chymotrypsin
Comments/Corrections

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