Document Detail

Effect of continuous and intermittent clenbuterol feeding on rat growth rate and muscle.
MedLine Citation:
PMID:  2566434     Owner:  NLM     Status:  MEDLINE    
1. The growth response to clenbuterol is a dynamic process. 2. Body weight gain is stimulated within two days of treatment and the effect attenuates by two weeks of treatment. 3. Intermittent feeding prevents the attenuation of the growth response. 4. Muscle weight increased 14-22% by both feeding regimens. 5. Clenbuterol decreased cathepsin B activity in the EDL and gastrocnemius and increased the activity in the soleus after two weeks of continuous clenbuterol treatment.
M A McElligott; A Barreto; L Y Chaung
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology     Volume:  92     ISSN:  0742-8413     ISO Abbreviation:  Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol.     Publication Date:  1989  
Date Detail:
Created Date:  1989-06-28     Completed Date:  1989-06-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8310013     Medline TA:  Comp Biochem Physiol C     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  135-8     Citation Subset:  IM    
Merck Sharp & Dohme Research Laboratories, Department of Physiology and Biochemistry, Rahway, NJ 07065.
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MeSH Terms
Acetylglucosaminidase / metabolism
Animal Feed
Body Weight / drug effects*
Cathepsin B / metabolism
Cathepsin D / metabolism
Clenbuterol / administration & dosage,  pharmacology*
Ethanolamines / pharmacology*
Muscles / drug effects*
Reg. No./Substance:
0/Ethanolamines; 37148-27-9/Clenbuterol; EC; EC B; EC D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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