Document Detail


Effect of combined oral contraceptives on bone mineral density in pre and postmenopausal women.
MedLine Citation:
PMID:  12148389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A retrospective urban-based cross-sectional study was done in the department of Pharmacology in collaboration with the department of Obs and Gynae of BSSMU, Dhaka, to define any relation between the OCP and BMD in pre and postmenopausal women. A total of 100 closely matched healthy women were selected non-randomly. The age range was 35-55 years. Among them 50 were controls or nonuser and 50 were case or users of OCP. They were further subdivided into pre and postmenopausal groups. Bone density of the 100 women was measured in distal radius and ulna by single photon Absorptiometry Bone Densitometer DTX-100. Statistically significant higher bone mineral density (BMD) was found in oral combined OCP users than non-users, both in pre and postmenopausal women. It can be concluded from this study that the most important non-contraceptive benefit of OCP may be positive effects on bone mass and thus reduced risk of postmenopausal osteoporosis and osteroporotic fracture.
Authors:
Sayeeda Sultana; Shahnaz Choudhury; S A R Choudhury
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mymensingh medical journal : MMJ     Volume:  11     ISSN:  1022-4742     ISO Abbreviation:  Mymensingh Med J     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-07-31     Completed Date:  2002-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9601799     Medline TA:  Mymensingh Med J     Country:  Bangladesh    
Other Details:
Languages:  eng     Pagination:  12-4     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, MMC, Mymensingh.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bone Density / drug effects*
Case-Control Studies
Contraceptives, Oral, Combined / pharmacology*
Cross-Sectional Studies
Female
Humans
Middle Aged
Postmenopause / physiology
Premenopause / physiology
Retrospective Studies
Chemical
Reg. No./Substance:
0/Contraceptives, Oral, Combined

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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