Document Detail


Effect of citrus lemon oil on growth and adherence of Streptococcus mutans.
MedLine Citation:
PMID:  23381618     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to exploit novel anticaries agents, we investigated the effects of citrus lemon oil (CLO), a type of natural product, on growth and adherence of the primary oral cariogenic bacteria Streptococcus mutans (S. mutans). The growth inhibitory effect was explored with a micro-dilution assay. Adherence was analyzed by colony counts on the respective surfaces and the adherence inhibition rate (AIR). Real time-PCR was used to investigate the effects of CLO on transcription of glucosyltransferase (Gtf) encoding genes, gtfB, C and D. Neson-Somogyi method was used to measure the effects of CLO on Gtf activity. The minimum inhibitory concentration of CLO against S. mutans was 4.5 mg/ml. The CLO effectively reduced the adherence of S. mutans on glass surface (the AIR were from 98.3 to 100 %, P > 0.05) and saliva-coated enamel surface (the AIR were from 54.8 to 79.2 %, P < 0.05). CLO effectively reduced the activity of Gtf and the transcription of gtfs in a dose dependent manner (P < 0.05). In conclusion, CLO can effectively inhibit the growth and the adherence to glass and saliva-coated enamel surfaces of S. mutans. It can also inhibit the transcription of gtfs, as well as the Gtf enzyme activity.
Authors:
Ying Liu; Xiangyu Zhang; Yuzhi Wang; Feifei Chen; Zhifen Yu; Li Wang; Shuanglu Chen; Maoding Guo
Related Documents :
20154398 - Assessment of e. coli and salmonella spp. infection risks associated with different fec...
7993588 - Illness associated with contamination of drinking water supplies with phenol.
115788 - Serotypes of beta-hemolytic treponema hyodysenteriae.
24631918 - (40)k in the black sea: a proxy to estimate biogenic sedimentation.
17877388 - (18)o/(16)o isotope effect on miscibility of isobutyric acid with water.
12603148 - Formation and structure of self-assembled monolayers of alkanethiolates on palladium.
Publication Detail:
Type:  Journal Article     Date:  2013-02-05
Journal Detail:
Title:  World journal of microbiology & biotechnology     Volume:  29     ISSN:  1573-0972     ISO Abbreviation:  World J. Microbiol. Biotechnol.     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-17     Completed Date:  2013-12-23     Revised Date:  2014-04-22    
Medline Journal Info:
Nlm Unique ID:  9012472     Medline TA:  World J Microbiol Biotechnol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1161-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / isolation & purification,  pharmacology*
Bacterial Adhesion / drug effects*
Citrus / chemistry*
Colony Count, Microbial
Gene Expression / drug effects
Gene Expression Profiling
Microbial Sensitivity Tests
Plant Oils / isolation & purification,  pharmacology*
Real-Time Polymerase Chain Reaction
Streptococcus mutans / drug effects*,  growth & development,  physiology
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Plant Oils; 0/lemon oil
Comments/Corrections
Erratum In:
World J Microbiol Biotechnol. 2014 Apr;30(4):1435

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Volatile fatty acids distribution during acidogenesis of algal residues with pH control.
Next Document:  Ovum transmigration after salpingectomy for ectopic pregnancy.