Document Detail

Effect of citric acid and citric acid-sucrose mixtures on swallowing in neurogenic oropharyngeal dysphagia.
MedLine Citation:
PMID:  14571326     Owner:  NLM     Status:  MEDLINE    
The ability of sour and sweet-sour mixtures to improve swallowing in 11 nursing home residents with neurogenic oropharyngeal dysphagia was investigated using fiberoptic endoscopic evaluation of swallowing. Citric acid (2.7%) significantly reduced aspiration and penetration compared with water. Teaspoon delivery of liquids significantly reduced aspiration and penetration compared with natural cup drinking. Subjects tended to appropriately self-regulate the cup volume they consumed after the first trial. A significant increase in spontaneous dry swallows was observed after both taste stimuli. The mechanisms for improved swallowing due to citric acid are not understood but may be due to increased gustatory and trigeminal stimulation of acid to the brainstem in neurologically impaired subjects.
Cathy A Pelletier; Harry T Lawless
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Dysphagia     Volume:  18     ISSN:  0179-051X     ISO Abbreviation:  Dysphagia     Publication Date:  2003  
Date Detail:
Created Date:  2003-10-22     Completed Date:  2003-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8610856     Medline TA:  Dysphagia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  231-41     Citation Subset:  D; IM    
Department of Food Science & Technology, Cornell University, Ithaca, New York, USA.
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MeSH Terms
Aged, 80 and over
Anticoagulants / administration & dosage*
Citric Acid / administration & dosage*
Deglutition / drug effects*,  physiology
Deglutition Disorders / drug therapy*,  etiology,  physiopathology
Drug Therapy, Combination
Middle Aged
Nervous System Diseases / complications*,  physiopathology
Oropharynx / drug effects*,  physiopathology
Sucrose / administration & dosage*
Reg. No./Substance:
0/Anticoagulants; 57-50-1/Sucrose; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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