Document Detail

Effect of cigarette smoking on copper, lead, and cadmium accumulation in human lens.
MedLine Citation:
PMID:  9613387     Owner:  NLM     Status:  MEDLINE    
AIM: To identify cigarette smoking as a risk factor for development of cataract, to determine the importance of copper, lead, and cadmium in cataractogenesis, and to learn about any relation between those elements. METHODS: Copper, lead, and cadmium concentrations were measured by atomic absorption spectrophotometry in 37 cataractous and nine normal human lenses. RESULTS: All three element accumulations in lenses with cataract were statistically meaningful. Lenticular copper, lead, and cadmium were increased significantly with cigarette smoking. Cadmium had a positive correlation both with lead and copper in cataractous lenses. CONCLUSION: The accumulation of copper, lead, and cadmium occurs in cataract. The probable source of cadmium in humans is cigarettes. Lenticular cadmium accumulation also increases copper and lead precipitation in the lens. Cigarette smoking might be cataractogenic.
O Cekic
Related Documents :
21357657 - Nonsteroidal antiinflammatory drug use and lower urinary tract symptoms: results from t...
15078667 - Trends in visual acuity impairment in us adults: the 1986-1995 national health intervie...
24390167 - Prevalence and causes of vision loss in east asia: 1990-2010.
15824227 - Anterior chamber depth and the risk of primary angle closure in 2 east asian populations.
10333617 - Do people who apply sunscreens, re-apply them?
20208017 - Case-control study of overweight, obesity, and colorectal cancer risk, overall and by t...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  82     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-06-11     Completed Date:  1998-06-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  186-8     Citation Subset:  IM    
Department of Ophthalmology, University of Ankara Medical School, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cadmium / analysis*
Case-Control Studies
Cataract / etiology*
Copper / analysis*
Lead / analysis*
Lens, Crystalline / chemistry*
Middle Aged
Risk Factors
Smoking / adverse effects*
Spectrophotometry, Atomic
Statistics, Nonparametric
Reg. No./Substance:
7439-92-1/Lead; 7440-43-9/Cadmium; 7440-50-8/Copper

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Platelet derived growth factor and fibroblast growth factor basic levels in the vitreous of patients...
Next Document:  A report by the British Orthopaedic Association/British Association of Plastic Surgeons Working Part...