Document Detail

Effect of chronic propranolol treatment on bone changes of secondary hyperparathyroidism in dialysis patients.
MedLine Citation:
PMID:  7177287     Owner:  NLM     Status:  MEDLINE    
To assess the effect of long-term propranolol therapy on uremic osteodystrophy, we evaluated retrospectively the biochemical, X-ray, and bone histological changes in 9 dialysed hypertensives who had been on propranolol treatment for periods ranging from 1 to 8 years. The control group included 9 well-matched dialysed uremics never treated with beta-blockers. The two groups did not differ in serum ionized calcium or iPTH levels. The incidence of bone resorption evaluated on X-ray findings and on bone biopsy specimens was of a comparable degree in the two groups. Our data show that propranolol even if started early in the course of renal failure, is of no benefit in preventing uremic bone disease.
F Pizzarelli; C Zoccali; C Ciccarelli; Q Maggiore; E Bonucci; P Ballanti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephron     Volume:  32     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1982  
Date Detail:
Created Date:  1983-02-14     Completed Date:  1983-02-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  93-4     Citation Subset:  IM    
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MeSH Terms
Bone Resorption / drug effects
Hyperparathyroidism, Secondary / drug therapy*
Kidney Failure, Chronic / complications*,  therapy
Propranolol / therapeutic use*
Renal Dialysis*
Renal Osteodystrophy / drug therapy*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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