Document Detail


Effect of chronic ipsilateral or contralateral intrauterine infusion of prostaglandin E2 (PGE2) on luteal function of unilaterally ovariectomized ewes.
MedLine Citation:
PMID:  7197035     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relationship between the chronic intrauterine injection of PGE2 every four hours adjacent or opposite to the corpus luteum on luteal function was studied. Intrauterine infusions every four hours of PGE2 (500 mug) from days 10 to 17 postestrus maintained luteal function only when infused into a uterine horn adjacent to a luteal-bearing ovary of unilaterally ovariectomized sheep with surgically separated uterine cornua. These data are compatible with the hypothesis that PGE2 is a good candidate for the antiluteolysin since it works only through a similar local pathway as the embryo during early pregnancy to sustain the corpus luteum.
Authors:
R R Magness; J M Huie; G L Hoyer; T P Huecksteadt; L P Reynolds; G J Seperich; G Whysong; C W Weems
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prostaglandins and medicine     Volume:  6     ISSN:  0161-4630     ISO Abbreviation:  Prostaglandins Med     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-11-24     Completed Date:  1981-11-24     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7810330     Medline TA:  Prostaglandins Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  389-401     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Castration*
Estrus
Female
Luteolysis / drug effects*
Pregnancy
Progesterone / blood
Prostaglandins E / administration & dosage*
Sheep
Uterus*
Chemical
Reg. No./Substance:
0/Prostaglandins E; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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