Document Detail


Effect of chronic intake of sweet substance on nociceptive thresholds and feeding behavior of Rattus norvegicus (Rodentia, Muridae).
MedLine Citation:
PMID:  16053245     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The investigation of the influence of sweetened food on feeding behavior targeted to non-sucrose nutrients as well as the sensitivity to painful stimuli in isolated and grouped animals is the aim of the present work. The tail withdrawal latencies in the tail-flick test (a spinal reflex) were measured before and immediately after the treatment with tap water or sucrose (62, 125 or 250 g/l). Our findings suggest that: (a) The analgesic effect of sucrose intake depends on the concentration of sucrose solution and on the time during which the solution is consumed; (b) the most effective concentration of sucrose followed by antinociceptive effect was the one of 250 g/l in both isolated and grouped animals; (c) considering the individually caged rats, the intake of sucrose in the highest concentration (250 g/l) was the smallest as compared with the consumption of sucrose in more diluted solutions (62.5 and 125 g/l), but this higher sweetened solution was followed by antinociception; (d) animals treated with concentrated sucrose solution ate smaller quantities of pellets than animals treated with tap water; (e) tonic intake of highly concentrated sweet substance seems to be crucial for the increase of the nociceptive threshold in our model of sweet substance-induced antinociception.
Authors:
E N Segato; E C C Rebouças; R L Freitas; M P T Caires; A V Cardoso; G C C Resende; G Shimizu-Bassi; D H Elias-Filho; N C Coimbra
Related Documents :
19339395 - Modulation of cognition and behavior in aged animals: role for antioxidant- and essenti...
9327465 - Review--animal waste used as livestock feed: dangers to human health.
23529735 - The animal food supplement sepiolite promotes a direct horizontal transfer of antibioti...
17673795 - Factors associated with practice decisions of nebraska veterinarians regarding type of ...
18325165 - Improving the nutritional status of elderly residents of long-term care homes.
12131045 - Confocal microscopy in multiple myeloma crystalline keratopathy.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nutritional neuroscience     Volume:  8     ISSN:  1028-415X     ISO Abbreviation:  Nutr Neurosci     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-08-01     Completed Date:  2005-09-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100892202     Medline TA:  Nutr Neurosci     Country:  England    
Other Details:
Languages:  eng     Pagination:  129-40     Citation Subset:  IM    
Affiliation:
Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, School of Medicine of Ribeirão Preto of the University of São Paulo (FMRP-USP), Avenue of Bandeirantes, 3900, Ribeirão Preto (SP) 14049-900, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Analgesia*
Animals
Dietary Sucrose / administration & dosage*
Drinking
Eating / drug effects*
Male
Nociceptors / physiology
Pain Measurement
Rats
Rats, Wistar
Solutions
Tail
Time Factors
Chemical
Reg. No./Substance:
0/Dietary Sucrose; 0/Solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chr...
Next Document:  Antimicrobial peptides in the oral environment: expression and function in health and disease.