Document Detail


Effect of chlorhexidine on plaque development in an artificial mouth.
MedLine Citation:
PMID:  17048     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of chlorhexidine on the development of plaque, resulting from the inoculation with saliva of a tooth mounted in an artificial mouth, has been studied. The agent delayed the formation of plaque and also inhibited changes in pH and Eh, whether sucrose was present or not. Applied as a rinse at intervals of 12 h it prevented formation of plaque and pH and Eh remained constant. Moreover, chlorhexidine inhibited pH and Eh changes in established plaque. A single application of a gel containing chlorhexidine also greatly inhibited plaque development.
Authors:
W A Coulter; C Russell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Microbios     Volume:  16     ISSN:  0026-2633     ISO Abbreviation:  Microbios     Publication Date:  1976  
Date Detail:
Created Date:  1977-07-18     Completed Date:  1977-07-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207257     Medline TA:  Microbios     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  21-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Biguanides / therapeutic use*
Chlorhexidine / administration & dosage,  therapeutic use*
Dental Plaque / microbiology,  prevention & control*
Gels
Humans
Hydrogen-Ion Concentration
Models, Biological
Mouth
Mouthwashes
Neisseria / growth & development
Saliva / microbiology
Species Specificity
Streptococcus / growth & development
Chemical
Reg. No./Substance:
0/Biguanides; 0/Gels; 0/Mouthwashes; 55-56-1/Chlorhexidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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