Document Detail

Effect of chlorhexidine on dental plaque and gingivitis in mentally retarded children.
MedLine Citation:
PMID:  1104246     Owner:  NLM     Status:  MEDLINE    
The purpose of the investigation was to determine the effect of chlorhexidine mouthrinses as a supplement to toothbrushing in the plaque control of mentally retarded children. Fifty-four mentally subnormal children 7-14 years of age took part in the investigation. During the first period, half of the children rinsed their mouths with 0.2% chlorhexidine gluconate solution twice a day. The rest of the children used a placebo mouthrinse. After a n 8-week interval a "cross-over" experiment was carried out during which a 0.1% chlorhexidine solution was used. Plaque and gingival indices were scored at the beginning of each period, after 3 weeks, and at the termination after 6 weeks. The results revealed that mouthrinses with 0.1% as well as 0.2% chlorhexidine gluconate reduced plaque and gingivitis in mentally retarded children. The results were statistically significant (P is less than 0.05) for both concentrations. Furthermore, the investigation confirmed the occurrence of certain side effects such as discoloration of teeth and tongues.
L M Bay; B G Russell
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Community dentistry and oral epidemiology     Volume:  3     ISSN:  0301-5661     ISO Abbreviation:  Community Dent Oral Epidemiol     Publication Date:  1975 Nov 
Date Detail:
Created Date:  1976-02-26     Completed Date:  1976-02-26     Revised Date:  2009-01-29    
Medline Journal Info:
Nlm Unique ID:  0410263     Medline TA:  Community Dent Oral Epidemiol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  267-70     Citation Subset:  D; IM    
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MeSH Terms
Biguanides / therapeutic use*
Chlorhexidine / adverse effects,  therapeutic use*
Clinical Trials as Topic
Dental Plaque / prevention & control*
Gingivitis / prevention & control*
Mental Retardation*
Mouthwashes / therapeutic use
Reg. No./Substance:
0/Biguanides; 0/Mouthwashes; 0/Placebos; 55-56-1/Chlorhexidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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