Document Detail

Effect of chemical sympathectomy on muscle blood flow.
MedLine Citation:
PMID:  562089     Owner:  NLM     Status:  MEDLINE    
Lumbar chemical sympathectomy using 5% phenol in glycerin alleviated intermittent claudication and improved cutaneous blood flow. This technic permits instituting physiotherapy and exercises to improve collateral circulation. The procedure was performed 56 times on 29 cases. No significant complication was observed. Muscle blood flow (MBF) was measured by 133Xe clearance, at rest and following exercise. Total blood flow (TBF) of the leg was measured by the impedance method, and increased cutaneous blood flow was confirmed by thermogram and photoplethysmogram. TBF increased significantly following exercise after sympathectomy. The ratio of MBF at rest and after exercise increased significantly in m. gastrocnemius, a white muscle, but was not significant in m. anterior tibialis, a red muscle. Chemical lumbar sympathectomy also produces preganglionic neurolysis to suppress vascular hypersensitivity after surgical ganglionectomy.
T Fujita; Y Kitani; T Nakamura; T Kimura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  56     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:    1977 Sep-Oct
Date Detail:
Created Date:  1977-11-25     Completed Date:  1977-11-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  653-60     Citation Subset:  IM; S    
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MeSH Terms
Collateral Circulation
Intermittent Claudication / therapy*
Leg / blood supply
Middle Aged
Muscles / blood supply*
Phenols / therapeutic use*
Physical Exertion
Regional Blood Flow
Sympathetic Nervous System / drug effects*
Reg. No./Substance:
0/Phenols; 56-81-5/Glycerol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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