Document Detail

Effect of carotid angioplasty and stenting on duplex velocity measurements in a porcine model.
MedLine Citation:
PMID:  19090631     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate if there are any differences in duplex ultrasound velocity measurements between native and stented carotid arteries using duplex ultrasound in an animal model. METHODS: The common carotid artery of 5 pigs was exposed bilaterally (10 arteries). Diameters and velocities were measured by ultrasound in the proximal, mid, and distal native artery at the intended site of stent implantation. Measurements were repeated after bilateral stent placement (Wallstent versus Precise) under angiographic control. Outcomes of native versus stented arteries and Wallstent versus Precise were statistically compared. RESULTS: Angiographic measurements matched well with duplex-measured diameters. The mean proximal stent diameter (3.5+/-0.5 mm) was significantly smaller than the native proximal artery diameter (4.2+/-0.4 mm, p = 0.004), mostly due to narrowing of the Wallstent diameter to 3.2+/-0.5 mm (p = 0.009). Proximal, mid, and distal segments of the Wallstents were narrower than those of the Precise stent, and associated peak systolic velocities (PSV) were higher at the 3 locations versus the Precise stent, although the differences were not statistically significant. Wallstent PSVs were higher than in the native artery at the proximal, mid, and distal segments, respectively; again, the differences were not statistically significant. CONCLUSION: Stent placement caused anatomical and hemodynamic alterations. Narrowings and associated increased velocities were noted. Such alterations, however, were stent-type dependent and did not justify a general approach to new velocity criteria indiscriminately applied to all stents.
Gert J de Borst; Rudy Meijer; Rob H Lo; Hans W G Vosmeer; Rob G A Ackerstaff; Frans L Moll
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists     Volume:  15     ISSN:  1526-6028     ISO Abbreviation:  J. Endovasc. Ther.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-18     Completed Date:  2009-03-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100896915     Medline TA:  J Endovasc Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-9     Citation Subset:  IM    
Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
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MeSH Terms
Angioplasty / adverse effects,  instrumentation*
Blood Flow Velocity
Carotid Artery, Common / physiopathology,  surgery*,  ultrasonography*
Laser-Doppler Flowmetry*
Models, Animal
Prosthesis Design
Radiography, Interventional
Regional Blood Flow
Treatment Outcome
Ultrasonography, Doppler, Duplex*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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