Document Detail


Effect of cardiopulmonary resuscitation compression rate on end-tidal carbon dioxide concentration and arterial pressure in man.
MedLine Citation:
PMID:  3125005     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The optimal rate of chest compression during CPR in man has been debated. Recently, the end-tidal carbon dioxide concentration (PetCO2) has been shown to correlate with cardiac output during CPR in experimental animals. Eighteen prehospital cardiac arrest patients were studied to determine the effect of external chest compression rate on the PetCO2 and BP in man when ventilation rate, ventilation inspiration time, applied compression force, and a 50:50 downstroke:upstroke ratio were held constant using a microprocessor-controlled CPR Thumper. Compression rate was increased from 60 to 140/min in 20 beat/min increments. The PetCO2 was 1.7 +/- 0.2% at a compression rate of 60/min and did not change significantly at increased rates. Systolic BP fell progressively from 59 +/- 5 mm Hg at 60/min to 46 +/- 4 mm Hg at 140/min. Diastolic BP remained approximately 23 mm Hg at all rates studied. Using a CPR manikin, we found that greater Thumper compression force was necessary to sustain the same sternal displacement and to achieve the same applied sternal pressure when the rate was increased due to a rate-limited fall in the compression duration.
Authors:
J P Ornato; E R Gonzalez; A R Garnett; R L Levine; B K McClung
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical care medicine     Volume:  16     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-04-07     Completed Date:  1988-04-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  241-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Pharmacy, Medical College of Virginia, Richmond 23298.
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MeSH Terms
Descriptor/Qualifier:
Aged
Blood Pressure*
Carbon Dioxide / blood*
Cardiac Output
Emergencies
Evaluation Studies as Topic
Female
Heart Arrest / blood,  therapy
Humans
Male
Microcomputers
Middle Aged
Models, Anatomic
Respiration, Artificial / methods
Resuscitation / methods*
Time Factors
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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