Document Detail


Effect of captopril on blood pressure and on the renin-angiotensin-aldosterone system in coarctation of the aorta.
MedLine Citation:
PMID:  6340859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSIONS: 1) MAP reduction and marked renin increase after captopril in COA patients support the view that systemic hypertension in COA is, at least in part, renin mediated and 2) the evaluation of PRA after captopril could be helpful in the decision to proceed with more invasive procedures in patients with suspicious clinical features of COA or with residual post-coarctectomy hypertension.
Authors:
F Fallo; I Maragno; P Merola; F Mantero
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical and experimental hypertension. Part A, Theory and practice     Volume:  5     ISSN:  0730-0077     ISO Abbreviation:  Clin Exp Hypertens A     Publication Date:  1983  
Date Detail:
Created Date:  1983-06-10     Completed Date:  1983-06-10     Revised Date:  2014-07-25    
Medline Journal Info:
Nlm Unique ID:  8207790     Medline TA:  Clin Exp Hypertens A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  321-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aldosterone / blood
Aortic Coarctation / complications,  physiopathology*
Blood Pressure / drug effects*
Captopril / pharmacology*,  therapeutic use
Dose-Response Relationship, Drug
Female
Humans
Hypertension / drug therapy,  etiology,  physiopathology
Male
Proline / analogs & derivatives*
Renin / blood
Renin-Angiotensin System / drug effects*
Chemical
Reg. No./Substance:
4964P6T9RB/Aldosterone; 9DLQ4CIU6V/Proline; 9G64RSX1XD/Captopril; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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