Document Detail


Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart.
MedLine Citation:
PMID:  3995543     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mitochondria isolated from heart tissue after a 1-min perfusion with Hanks medium were found to have significantly lower rates of State-3 respiration and respiratory control ratios compared to mitochondria isolated from non-perfused hearts. Examination of the mitochondrial preparations by electron microscopy revealed that a large proportion of the mitochondria isolated from perfused heart tissue were swollen and broken compared to mitochondria from non-perfused hearts.
Authors:
J L Staecker; M J Nadakavukaren; A Richardson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cell and tissue research     Volume:  240     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1985  
Date Detail:
Created Date:  1985-07-24     Completed Date:  1985-07-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  247-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adenosine Triphosphate / biosynthesis
Animals
Coronary Circulation*
Culture Media
Male
Mitochondria, Heart / metabolism,  physiology,  ultrastructure*
Oxygen Consumption
Perfusion*
Rats
Rats, Inbred F344
Grant Support
ID/Acronym/Agency:
AG 01548/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Culture Media; 56-65-5/Adenosine Triphosphate

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