Document Detail

Effect of botulinum toxin type A, motor imagery and motor observation on motor function of hemiparetic upper limb after stroke.
MedLine Citation:
PMID:  20569045     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In rehabilitation settings, motor imagery, motor observation and mirror therapy serve as techniques for the recovery of paretic upper limb in patients with movement disorders after stroke, whereas botulinum toxin type A (BTX-A) offers the best treatment for focal spasticity.
CASE REPORTS: After haemorrhagic stroke, three patients (two men and one woman, mean age: 61.2 +/- 7.03) presented with hemiparesis of the left or right hand and arm with flexion of fingers, wrist and elbow, with no disturbance to sensitivity but with loss of use handoff the limb to write, eat or dress. After BTX-A injections, the patients underwent a daily rehabilitation programme based on motor imagery and motor observation for 1 month. Before and after the combined treatment, the motor function, spasticity and functional deficits of the patient were extensively measured. After a 3-month follow-up, upper limb spasticity measured with the Modified Ashworth Scale had worsened, yet the associated score remained lower than that at baseline. However, in these three patients a large improvement of motor function of the hemiparetic upper limb was observed.
CONCLUSION: Combined treatment may be a viable rehabilitation option in post-stroke patients with disability to upper-extremity motor function, however further investigations are needed to determine its reproducibility in larger case series or clinical trials.
Andrea Santamato; Francesco Panza; Serena Filoni; Maurizio Ranieri; Vincenzo Solfrizzi; Vincenza Frisardi; Annarita Dellomonaco; Maria Teresa Amoruso; Loredana Amoruso; Patrick G Kehoe; Marisa Megna; Pietro Fiore
Related Documents :
25409675 - Fatty meal ultrasonography in chronic acalculous cholecystitis.
8597995 - Prognosis of individuals with atrial fibrillation.
15897635 - Nocturnal polyuria with abnormal circadian rhythm of plasma arginine vasopressin in pos...
19444535 - Course of matrix metalloproteinase-9 isoforms after the administration of uric acid in ...
1909275 - Treatment of chronic hepatitis c with weekly administration of interferon-alpha.
25372535 - Subclinical hypercortisolism in central serous chorioretinopathy.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Brain injury     Volume:  24     ISSN:  1362-301X     ISO Abbreviation:  Brain Inj     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-09     Completed Date:  2010-12-30     Revised Date:  2014-11-14    
Medline Journal Info:
Nlm Unique ID:  8710358     Medline TA:  Brain Inj     Country:  England    
Other Details:
Languages:  eng     Pagination:  1108-12     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Botulinum Toxins, Type A / therapeutic use*
Middle Aged
Muscle Spasticity / drug therapy*,  physiopathology
Neuromuscular Agents / therapeutic use*
Paresis / drug therapy*,  physiopathology,  rehabilitation
Stroke / drug therapy*,  physiopathology,  rehabilitation
Treatment Outcome
Upper Extremity / physiopathology*
Reg. No./Substance:
0/Neuromuscular Agents; EC Toxins, Type A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Social inclusion of persons with moderate head injuries: the points of view of adolescents with brai...
Next Document:  Low-frequency rTMS with language therapy over a 3-month period for sensory-dominant aphasia: case se...