Document Detail

Effect of blood sampling schedule on the ability to discriminate between postprandial glycemic responses.
MedLine Citation:
PMID:  19729129     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The blood glucose responses elicited by foods are often determined using blood samples taken at 15-min intervals. Our objective was to see whether taking blood samples at 10-min intervals affected the results. METHODS: Overnight-fasted healthy subjects (n=11) were studied on nine different occasions with seven different test meals. Blood samples were obtained at fasting and at 10, 15, 20, 30, 40, 45, 50, 60, 90, and 120 min after starting to eat. Peak rise, incremental area under the curve, and relative glycemic response were calculated using the 10- and 15-min sampling schedules. RESULTS: With 10-min intervals, peak rise was 4% greater than with 15-min intervals (P<0.001), but sampling interval did not significantly affect mean incremental area under the curve or relative glycemic response. The 10-min blood sampling schedule had a slightly greater ability to discriminate between foods and between subjects for peak rise and relative glycemic response. CONCLUSIONS: We conclude that the blood sampling schedule used may influence the accuracy and precision of measurements of glycemic response; however, the difference between taking blood samples at 10-min and 15-min intervals is quite small.
Janice L Lui; Xiaomiao Lan-Pidhainy; Yolanda Brummer; Susan M Tosh; Peter J Wood; Thomas M S Wolever
Related Documents :
2111039 - Long-term preservation of blood samples for diagnosis of trypanosoma cruzi infection.
17194129 - Microfluidic flow-flash: method for investigating protein dynamics.
18771669 - Assessment of sample collection and storage methods for multicenter immunologic researc...
20441869 - Polypyrrole solid phase microextraction: a new approach to rapid sample preparation for...
17522849 - A critical comparison of analytical flow systems exploiting streamlined and pulsed flows.
18989489 - Observational study to determine factors associated with blood sample haemolysis in the...
17921009 - Blood component therapy in obstetrics.
10552079 - 99mtc-mama-chrysamine g, a probe for beta-amyloid protein of alzheimer's disease.
21656779 - Pulsed wave doppler ultrasonography for the assessment of peripheral vasomotor response...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  25     ISSN:  1873-1244     ISO Abbreviation:  -     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-04     Completed Date:  2009-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1064-6     Citation Subset:  IM    
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Glucose / analysis*
Blood Specimen Collection*
Dietary Carbohydrates / administration & dosage
Eating / physiology
Postprandial Period / physiology*
Time Factors
Reg. No./Substance:
0/Blood Glucose; 0/Dietary Carbohydrates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The impact of physical exercise on calcium balance in healthy subjects during prolonged hypokinesia.
Next Document:  Image gently, step lightly: increasing radiation dose awareness in pediatric interventions through a...