Document Detail


Effect of blackcurrant-, cranberry- and plum juice consumption on risk factors associated with kidney stone formation.
MedLine Citation:
PMID:  12373623     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the influence of plum-, cranberry- and blackcurrant juice on urinary stone risk factors. DESIGN: Investigations were carried out in 12 healthy male subjects aged 18-38 y. All subjects received a standardized diet formulated according to the dietary recommendations of the German Society of Nutrition. The subjects provided 24 h urine collections in a control, three loading phases. In each loading phase a neutral mineral water was substituted for 330 ml of the particular juice. RESULTS: Cranberry juice decreased the urinary pH, whereas the excretion of oxalic acid and the relative supersaturation for uric acid were increased. Blackcurrant juice increased the urinary pH and the excretion of citric acid. The excretion of oxalic acid was increased too. All changes were statistically significant. The plum juice had no significant effect on the urinary composition. CONCLUSION: It is concluded that blackcurrant juice could support the treatment and metaphylaxis of uric acid stone disease because of its alkalizing effect. Since cranberry juice acidifies urine it could be useful in the treatment of brushite and struvite stones as well as urinary tract infection. SPONSORSHIP: Funded by our own Division respectively the University.
Authors:
T Kessler; B Jansen; A Hesse
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  56     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-10-09     Completed Date:  2002-12-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  1020-3     Citation Subset:  IM    
Affiliation:
Division of Experimental Urology, Department of Urology, University of Bonn, Bonn, Germany. Kessler@Uni-Bonn.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Beverages*
Citric Acid / urine
Diet
Humans
Hydrogen-Ion Concentration
Kidney Calculi / etiology*,  prevention & control,  urine
Male
Prunus*
Ribes*
Risk Factors
Urinalysis
Vaccinium macrocarpon*
Chemical
Reg. No./Substance:
77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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