Document Detail


Effect of bifidobacteria feeding on fecal flora and production of immunoglobulins in lactating mouse.
MedLine Citation:
PMID:  10100899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To elucidate the effects of probiotics on the stimulation of immunoglobulin production during lactation, feeding trials of bifidobacteria in lactating mice were conducted. Bifidobacteria appeared in feces at 9.67+/-0.17 log 10 number per gram levels. All bifidobacteria found in the feces were the administered strain. Mice fed bifidobacteria for 12 days showed significantly high levels of fecal total IgA compared to that of the control group (P < 0.05). The levels of anti-beta-lactoglobulin IgA in milk as well as in fecal extracts were significantly higher in the bifidobacteria-fed group than that of the control group (P < 0.05). These results suggest that the intake of bifidobacteria can enhance local production of IgA in milk and the intestine, which may help to protect both pups and dams from exposure to food antigens.
Authors:
Y Fukushima; Y Kawata; K Mizumachi; J Kurisaki; T Mitsuoka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of food microbiology     Volume:  46     ISSN:  0168-1605     ISO Abbreviation:  Int. J. Food Microbiol.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-05-27     Completed Date:  1999-05-27     Revised Date:  2006-04-13    
Medline Journal Info:
Nlm Unique ID:  8412849     Medline TA:  Int J Food Microbiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  193-7     Citation Subset:  IM    
Affiliation:
Scientific Liaison Office, Nestlé Japan Ltd., Tokyo. qzc04363@niftyserve.or.jp
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MeSH Terms
Descriptor/Qualifier:
Animals
Bifidobacterium / physiology*
Colony Count, Microbial
Enzyme-Linked Immunosorbent Assay
Feces / microbiology*
Female
Immunoglobulin A / biosynthesis*,  blood
Lactation
Mice
Mice, Inbred C3H
Milk / immunology
Probiotics / metabolism*
Specific Pathogen-Free Organisms
Chemical
Reg. No./Substance:
0/Immunoglobulin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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