| Effect of balloon inflation time on expansion of sirolimus-eluting stent. | |
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MedLine Citation:
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PMID: 19784815 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is little information about the relationship between balloon inflation time and sirolimus-eluting stent (SES) expansion. In this randomized intravascular ultrasound (IVUS) study, 92 de novo lesions in native coronary arteries that underwent SES implantation were enrolled. Sirolimus-eluting stent was implanted using an inflation pressure of 14 atm. Stent balloon was gradually inflated until 14 atm in 10 s. In the short inflation group, it was deflated immediately after an image of the balloon inflated at 14 atm was taken. Stent balloon inflation lasted 60 s in the long inflation group. Intravascular ultrasound was then performed. The long balloon inflation resulted in a larger stent cross-sectional area (4.9 +/- 1.6 mm(2) vs 4.3 +/- 1.4 mm(2), P < 0.05) and expansion (71% +/- 13% vs 60% +/- 13%, P < 0.001) compared to the short balloon inflation, although stent expansion was relatively low in both groups. The relatively longer balloon inflation time using an inflation pressure of 14 atm results in better SES expansion. However, in the majority of lesions, adequate stent expansion is not achieved even using long balloon inflation, if it is inflated at 14 atm. |
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Authors:
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Tatsuhiko Asano; Yoshio Kobayashi; Kenichi Fukushima; Yo Iwata; Hideki Kitahara; Naoki Ishio; Takashi Nakayama; Nakabumi Kuroda; Issei Komuro |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial Date: 2009-09-27 |
Journal Detail:
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Title: Heart and vessels Volume: 24 ISSN: 1615-2573 ISO Abbreviation: Heart Vessels Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-09-28 Completed Date: 2009-12-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511258 Medline TA: Heart Vessels Country: Japan |
Other Details:
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Languages: eng Pagination: 335-9 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chuo-ku, Chiba, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary / instrumentation* Cardiovascular Agents / administration & dosage* Coronary Artery Disease / therapy*, ultrasonography Drug-Eluting Stents* Female Humans Male Middle Aged Pressure Prospective Studies Prosthesis Design Sirolimus / administration & dosage* Time Factors Treatment Outcome Ultrasonography, Interventional |
| Chemical | |
Reg. No./Substance:
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0/Cardiovascular Agents; 53123-88-9/Sirolimus |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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