Document Detail


Effect of autoimmune thyroid disease in older euthyroid infertile woman during the first 35 days of an IVF cycle.
MedLine Citation:
PMID:  21047632     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this case-control study of euthyroid first-cycle IVF patients ≥ 38 years old with singleton baby, miscarriage, biochemical pregnancy, and no pregnancy outcomes from 2005-2008, we assayed frozen serum for autoimmune thyroid disease (AITD) and thyroid function at cycle start, trigger, and 4 and 5 weeks' gestation. AITD prevalence in older infertile women was similar across clinical outcomes, and although AITD was associated with a higher baseline TSH, TSH remained within acceptable ranges, suggesting that T(4) supplementation may not affect maternal outcomes in older euthyroid AITD patients through 5 weeks gestation.
Authors:
Andrea Reh; Sonal Chaudhry; Felicia Mendelsohn; Shelly Im; Linda Rolnitzky; Alana Amarosa; Mortimer Levitz; Suman Srinivasa; Lewis Krey; Alan S Berkeley; James A Grifo; Ann Danoff
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-11-03
Journal Detail:
Title:  Fertility and sterility     Volume:  95     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-22     Completed Date:  2011-04-22     Revised Date:  2012-03-07    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1178-81     Citation Subset:  IM    
Copyright Information:
Published by Elsevier Inc.
Affiliation:
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, New York University Fertility Center, New York, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous / epidemiology
Adult
Case-Control Studies
Female
Fertilization in Vitro / statistics & numerical data*
Humans
Hypothyroidism / epidemiology
Infertility, Female / epidemiology*,  therapy
Maternal Age
Pregnancy
Pregnancy Outcome / epidemiology*
Prevalence
Thyroid Gland / physiology*
Thyroiditis, Autoimmune / epidemiology*
Grant Support
ID/Acronym/Agency:
1UL1RR029893/RR/NCRR NIH HHS; UL1 RR029893-01/RR/NCRR NIH HHS

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