| Effect of aspect ratio on chemical reactions on microchip. | |
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MedLine Citation:
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PMID: 17096000 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Parallel two-phase laminar flow, which is formed when two solutions flow in microchannels, has been developed and has advanced unique research in the area of microchip analysis. In two-phase laminar flow, channel size has a significant effect on the efficiency of chemical reactions. However, the sizes of microchannels vary greatly in many studies. In this paper, we report on the effect of microchannel size on chemical reactions on a microchip. Aspect ratio is defined as the ratio of depth to width of a microchannel. Five microchips with different aspect ratios (from 0.50 to 2.00) were fabricated by mechanical machining. The reaction of nitrous acid and Saltzman reagent was carried out on these microchips and the absorbance was measured on-line in a capillary tube, which was attached to the outlet on the microchip. The results showed that the color reaction occurred more efficiently as the aspect ratio increased. This result is expected to be useful when determining the size of microchannels. |
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Authors:
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Takahiro Shimizu; Hiroyuki Masaki; Takashi Korenaga |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Environmental sciences : an international journal of environmental physiology and toxicology Volume: 13 ISSN: 0915-955X ISO Abbreviation: Environ Sci Publication Date: 2006 |
Date Detail:
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Created Date: 2006-11-10 Completed Date: 2007-03-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9209787 Medline TA: Environ Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 263-9 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Ohsawa, Hachioji, Tokyo 192-0397, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ethylenediamines
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chemistry Microchip Analytical Procedures* Nitrous Acid / chemistry Phosphoric Acids / chemistry Sulfanilic Acids / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Ethylenediamines; 0/Phosphoric Acids; 0/Sulfanilic Acids; 551-09-7/N-(1-naphthyl)ethylenediamine; 7664-38-2/phosphoric acid; 7782-77-6/Nitrous Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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