Document Detail

Effect of aquatic exercise training on fatigue and health-related quality of life in patients with multiple sclerosis.
MedLine Citation:
PMID:  22609300     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the effectiveness of aquatic exercise training on fatigue and health-related quality of life (HRQOL) in women with multiple sclerosis (MS).
DESIGN: Randomized controlled trial, 4-week and 8-week follow-up.
SETTING: Referral center of a multiple sclerosis society.
PARTICIPANTS: Women (N=32) diagnosed with relapsing-remitting MS (mean age ± SD, 32.6±8.0y) were recruited into this study. After undergoing baseline testing by a neurologist, participants were randomly assigned to either an intervention (aquatic exercise) or a control group.
INTERVENTIONS: The intervention consisted of 8 weeks supervised aquatic exercise in a swimming pool (3 times a week, each session lasting 60min).
MAIN OUTCOME MEASURES: At baseline, 4 weeks, and 8 weeks, fatigue and HRQOL were assessed by a blind assessor using the Modified Fatigue Impact Scale and the Multiple Sclerosis Quality of Life-54 questionnaire, respectively. A mixed-model approach to repeated-measures analysis of variance was used to detect within- and between-subject effects.
RESULTS: Findings are based on 21 patients (10 from the exercise group and 11 from the control group) who had data available on outcomes. There was no significant difference between the 2 groups at the baseline. Patients in the aquatic exercise group showed significant improvements in fatigue and subscores of HRQOL after 4 and 8 weeks compared with the control group. Results obtained from the intention-to-treat analysis were consistent with those of per-protocol analysis.
CONCLUSIONS: The findings suggest that aquatic exercise training can effectively improve fatigue and HRQOL of patients with MS and should be considered in the management of this relatively common public health problem.
Mehdi Kargarfard; Masoud Etemadifar; Peter Baker; Maryam Mehrabi; Reza Hayatbakhsh
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2012-05-16
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  93     ISSN:  1532-821X     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-19     Completed Date:  2012-11-30     Revised Date:  2013-02-07    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1701-8     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Faculty of Physical Education and Sport Sciences, University of Isfahan, Isfahan, Iran.
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MeSH Terms
Analysis of Variance
Disability Evaluation
Exercise Therapy / methods*
Fatigue / rehabilitation*
Hydrotherapy / methods*
Multiple Sclerosis / rehabilitation*
Quality of Life*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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