Document Detail

Effect of anesthetics containing lidocaine and epinephrine on cardiovascular changes during dental implant surgery.
MedLine Citation:
PMID:  17520951     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to evaluate cardiovascular changes during dental implant surgery using 2% lidocaine with 1:80 000 epinephrine. Eleven normotensive subjects, ranging from 18 to 56 years, were selected to undergo dental implant surgery in the jaw. They were monitored in the pre-, intra-, and postsurgical periods by continuous noninvasive automatic arterial pressure and cardiac frequency measurements taken every 2 minutes. Parameter scores were obtained for the following phases: P1, 15 minutes during preparation of the patient (control period); P2, before anesthesia; P3, immediately after anesthesia; P4, 2 minutes into anesthesia; P5, during incision and detachment; P6, during perforation; P7, during implant placement; P8, during suturing; P9, on completion; and P10, 10 minutes after termination. Individualized statistical analysis for each group during the pre-, intra-, and postoperative periods were performed by analysis of variance. The greatest variations in systolic pressure were increases of 2.29% during phase P2 and 2.59% in phase P5. Diastolic pressure decreased during phase P6 (-2.58%) and increased in P10 (3.27%). The greatest changes in heart rate occurred in phase P10 (-3.24%). There were no statistically significant changes among the evaluated phases (P > .05). In conclusion, there were no changes in the analyzed cardiocirculatory parameters during dental implant surgery (systolic, diastolic, and mean arterial blood pressures and heart rate) in normotensive subjects anesthetized with 2% lidocaine with epinephrine 1:80000.
Fátima N Faraco; Paulo Y Kawakami; Maria J Mestnik; Daniel S Ferrari; Jamil A Shibli
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of oral implantology     Volume:  33     ISSN:  0160-6972     ISO Abbreviation:  J Oral Implantol     Publication Date:  2007  
Date Detail:
Created Date:  2007-05-24     Completed Date:  2007-08-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801086     Medline TA:  J Oral Implantol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  84-8     Citation Subset:  D    
Department of Peridontics and Implantology, School of Dentistry, University of Santo Amaro, SP, Brazil.
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MeSH Terms
Analysis of Variance
Anesthesia, Dental*
Anesthetics, Local / pharmacology
Blood Pressure / drug effects*
Dental Implantation, Endosseous*
Epinephrine / pharmacology
Heart Rate / drug effects*
Lidocaine / pharmacology
Middle Aged
Vasoconstrictor Agents / pharmacology
Reg. No./Substance:
0/Anesthetics, Local; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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