Document Detail

Effect of anaesthetic agents administered to the mothers on transcutaneous bilirubin levels in the neonates.
MedLine Citation:
PMID:  20219048     Owner:  NLM     Status:  MEDLINE    
AIM: To investigate the effect of anaesthetic agents on transcutaneous bilirubin levels during the first 24 h in neonates delivered by caesarean section. METHODS: A total of 168 neonates delivered by caesarean section, during which sevoflurane was used for general anaesthesia (group A), bupivacaine for spinal anaesthesia (group B), levobupivacaine for epidural anaesthesia (group C) and 155 neonates delivered vaginally were included in the study. Transcutaneous bilirubin levels (TBLs) of infants were measured during the first 24 h and compared with each other. RESULTS: The TBLs in neonates delivered vaginally were higher than those delivered by caesarean section, but the difference was not significant. TBLs were higher in groups A and C than in group B (p = 0.034, p = 0.011 respectively). TBLs were higher in group C than in group A, but the difference was not significant (p > 0.05). When the groups were compared with vaginal delivery group, TBLs in groups A and C were found higher (p = 0.03, p = 0.022 respectively). CONCLUSION: The route of delivery had no effect on TBL. While bupivacaine was found to have no effect on neonatal bilirubin levels, levobupivacaine increased neonatal biluribin levels, but further studies are needed for definite results.
S Alkan; U Tiraş; Y Dallar; D Sunay
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2010-04-26
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  99     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-08-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  993-6     Citation Subset:  IM    
Department of Family Medicine, Ankara Training and Research Hospital, Ministry of Health, Ankara, Turkey.
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MeSH Terms
Anesthesia, Conduction
Anesthesia, General
Anesthesia, Obstetrical / adverse effects*
Anesthetics / adverse effects*
Bilirubin / blood
Bupivacaine / adverse effects,  analogs & derivatives
Cesarean Section*
Hyperbilirubinemia, Neonatal / chemically induced*
Infant, Newborn
Methyl Ethers / adverse effects
Reg. No./Substance:
0/Anesthetics; 0/Methyl Ethers; 0/levobupivacaine; 2180-92-9/Bupivacaine; 28523-86-6/sevoflurane; 635-65-4/Bilirubin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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