Document Detail


Effect of amnioinfusion for meconium stained amniotic fluid on perinatal outcome.
MedLine Citation:
PMID:  15366799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To see the effect of amnioinfusion on perinatal outcome in cases of meconium staining of liquor. METHODS: This study was conducted in department of Obstetrics and Gynaecology, unit 1, Jinnah Postgraduate Medical Centre, Karachi, from 1st January 1998 to 31st December 2000. Four hundred patients were included in this study, assigning 200 for amnioinfusion and 200 as control. All patients were matched in both the groups with respect to age, antenatal booking, parity, gestational age, stage of labour, colour of amniotic fluid and fetal birth weight. Both the groups were found to be comparable. RESULTS: The rate of Caesarean section was found to be 37% in amnioinfusion group, which collaborates with other international studies. The fetal outcome was better i.e. 91% alive and healthy, after amnioinfusion due to dilution of meconium stained amniotic fluid with physiological solutions. The perinatal outcome was recorded by Apgar score at 5 minutes. The perinatal morbidity and mortality both were significantly lowered and was found to be 6% as compared to 14% in control, which was also noticed by less number of admissions in nursery i.e. 12% and perinatal deaths. The incidence of meconium aspiration syndrome was found to be 56% in control and was reduced to 22% after amnioinfusion in the other arm of the study. CONCLUSION: These results are very encouraging and suggestion can be safely made that in future amnioinfusion will be the ideal method of preventing fetal distress due to meconium stained amniotic fluid.
Authors:
F Ashfaq; A A Shah
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  54     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-09-15     Completed Date:  2004-10-21     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  322-5     Citation Subset:  IM    
Affiliation:
Sindh Government Qatar Hospital, Karachi.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniotic Fluid / metabolism
Apgar Score
Birth Weight
Case-Control Studies
Cesarean Section
Delivery, Obstetric / methods
Female
Fetus / metabolism
Gestational Age
Humans
Infant, Newborn
Infusions, Parenteral
Meconium Aspiration Syndrome / prevention & control
Oligohydramnios / therapy*
Pregnancy
Pregnancy Outcome*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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