Document Detail


Effect of aminonucleoside on the stability of rat liver ribosomal RNA to heating.
MedLine Citation:
PMID:  1027546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
High molecular weight ribosomal RNA has been isolated from normal rat liver and from the livers of rats treated with aminonucleoside. Melting curves of the rRNA from treated rat livers were shifted to higher temperatures. The melting temperatures were found to be 62.5 and 66 degrees C for normal and treated material respectively. The rRNA was heated at different temperatures and analysed by polyacrylamide gel electrophoresis. In both normal and treated material, the 18 S was more stable in the treated material when compared with the control material.
Authors:
S D Kung; M Mitranic; M A Moscarello
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cytobios     Volume:  16     ISSN:  0011-4529     ISO Abbreviation:  Cytobios     Publication Date:  1976  
Date Detail:
Created Date:  1977-09-02     Completed Date:  1977-09-02     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0207227     Medline TA:  Cytobios     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  163-70     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Drug Stability
Hot Temperature*
Liver / analysis,  drug effects*
Male
Molecular Weight
Puromycin / analogs & derivatives*
Puromycin Aminonucleoside / pharmacology*
RNA, Ribosomal* / analysis
Rats
Chemical
Reg. No./Substance:
0/RNA, Ribosomal; 53-79-2/Puromycin; 58-60-6/Puromycin Aminonucleoside

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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