Document Detail


Effect of altered loading conditions during haemodialysis on left ventricular filling pattern.
MedLine Citation:
PMID:  8508859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Changes in the circulating volume associated with haemodialysis result in modification of left ventricular loading conditions. To determine the influence of haemodialysis on Doppler indices of left ventricular filling, 12 patients (mean age 40.8 +/- 2.7 (SEM) years) with renal insufficiency but without overt heart disease were studied by Doppler-echocardiography immediately before and after haemodialysis. Haemodialysis resulted in a decrease in body weight from 68.0 +/- 3.8 kg to 65.0 +/- 3.7 kg (P < 0.01). Heart rate and blood pressure did not change significantly during haemodialysis. Left ventricular diastolic dimension (M-mode) decreased from 53.5 +/- 1.1 mm to 49.5 +/- 1.9 mm (P < 0.05), whereas the shortening fraction did not change. Haemodialysis elicited marked changes in the early diastolic rapid filling wave (E wave) recorded by pulsed Doppler at the level of the mitral annulus. Peak velocity of the early rapid filling phase (peak E) decreased significantly from 95.3 +/- 8.2 cm.s-1 to 63.0 +/- 5.7 cm.s-1 (P < 0.001) and mid-diastolic deceleration of transmitral velocity decreased from 437.3 +/- 54.2 cm.s-2 to 239.7 +/- 54.4 cm.s-2 (P < 0.01). The peak filling velocity during atrial contraction (peak A) did not change (79.7 +/- 6.3 cm.s-1 vs 74.1 +/- 4.7 cm.s-1; P = NS). The ratio peak E/peak A decreased from 1.19 +/- 0.06 to 0.85 +/- 0.04 (P < 0.01) during haemodialysis. The results provide further evidence for the pronounced preload-dependence of Doppler indices of left ventricular diastolic function.
Authors:
J Sztajzel; P Ruedin; C Monin; C Stoermann; M Leski; W Rutishauser; R Lerch
Related Documents :
742729 - Hemodynamic effects of phentolamine in valvular abnormalities.
6186859 - Effect of disopyramide on left ventricular performance: the relationship of free and to...
17512359 - Central sleep apnea, right ventricular dysfunction, and low diastolic blood pressure ar...
12574739 - Effects of dobutamine on left ventricular shape and geometry: an easy way to detect the...
2953239 - Vasodilators and regression of left ventricular hypertrophy. hydralazine versus prazosi...
6211969 - Early hypertension and cardiac work.
6427499 - Open-loop analysis of paco2 oscillation in the dog.
6862579 - Effects of withdrawing diuretic therapy on blood pressure in mild hypertension.
2274319 - Blood pressure abnormalities as background roles for vertigo, dizziness and disequilibr...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European heart journal     Volume:  14     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-07-15     Completed Date:  1993-07-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  655-61     Citation Subset:  IM    
Affiliation:
Cardiology Center, University Hospital, Geneva, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity / physiology
Blood Pressure / physiology*
Blood Volume / physiology*
Cardiac Volume / physiology
Echocardiography, Doppler
Female
Heart Rate / physiology
Hematocrit
Humans
Kidney Failure, Chronic / physiopathology*,  therapy
Male
Middle Aged
Mitral Valve / physiopathology
Myocardial Contraction / physiology
Renal Dialysis*
Ventricular Function, Left / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The sinus node function: normal and pathological.
Next Document:  Discrepancy between systolic and diastolic dysfunction of the left ventricle in patients with Duchen...