Document Detail


Effect of alterations in femoral artery flow on abdominal vessel hemodynamics in swine.
MedLine Citation:
PMID:  10690272     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In support of an in vivo investigation in swine of the influence of changes in fluid dynamic wall shear on arterial macromolecular permeability, a procedure has been developed to alter the flows in the porcine posterior arterial vasculature by opening and closing a reversible arteriovenous shunt placed on one of the femoral arteries. Laparoscopic techniques were used to place appropriately modified Transonic Systems ultrasonic flow probes on both external and circumflex iliac arteries, and on the terminal aorta. Flow measurements were made prior to shunt placement, and with the shunt open and closed, to measure the influence of altered external iliac artery flow on the distribution to the infrarenal abdominal vessels. Similar experiments were carried out to relate the flow rates in the external iliac arteries to those in the femoral arteries, which are more accessible. Based on the relationships among the measured flow rates, rules have been developed to estimate the major infrarenal flows in the pig, at baseline and with the shunt opened and closed, from only the flow rates measured at the two femoral arteries.
Authors:
J M Henderson; J A Aukerman; P A Clingan; M H Friedman
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biorheology     Volume:  36     ISSN:  0006-355X     ISO Abbreviation:  Biorheology     Publication Date:  1999  
Date Detail:
Created Date:  2000-03-09     Completed Date:  2000-03-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372526     Medline TA:  Biorheology     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  257-66     Citation Subset:  IM    
Affiliation:
Biomedical Engineering Center, Ohio State University, Columbus 43210, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Arteriovenous Shunt, Surgical
Femoral Artery / physiology*,  ultrasonography
Hemodynamics
Hemorheology*
Iliac Artery / physiology,  ultrasonography
Regional Blood Flow
Stress, Mechanical
Swine
Grant Support
ID/Acronym/Agency:
HL29095/HL/NHLBI NIH HHS; HL50442/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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