Document Detail


Effect of age, sex and parity on anorectal function.
MedLine Citation:
PMID:  7827909     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ninety-one healthy subjects (51 women; age range 16-85 years) were studied prospectively to determine the effect of age, sex and parity on anorectal function. Maximum resting pressure, voluntary contraction pressure, rectal sensation to distension, rectal and mid-anal electrosensitivity, perineal descent, pudendal nerve terminal motor latency and fibre density of the external and sphincter were measured. Sex influenced mean(s.d.) voluntary contraction pressure (148(56) versus 95(43) cmH2O for men versus women, P < 0.0001), perineal descent on straining (1.0(0.5) versus 1.3(0.4) cm, P = 0.02) and fibre density (1.43(0.14) versus 1.52(0.15), P = 0.02). Age influenced resting pressure (r = -0.43, P = 0.0001), perineal position at rest (r = -0.55, P < or = 0.0001), mid-anal electrosensitivity (r = 0.42, P = 0.0001) and rectal electrosensitivity (r = 0.54, P < 0.0001). Parity affected mean(s.d.) voluntary contraction pressure (105(53) versus 75(20) cmH2O for nulliparous versus parous women, P = 0.04) and mid-anal electrosensitivity (5.3(2.3) versus 4.5(2.3) mA, P = 0.02). Increasing age leads to perineal descent at rest, slowed pudendal nerve conduction, a fall in resting anal pressure and decreased anorectal sensory function. Women have a lower and squeeze pressure, greater perineal descent, longer pudendal nerve terminal motor latency and a greater muscle fibre density than men. Parity leads only to lower squeeze pressure.
Authors:
J S Jameson; Y W Chia; M A Kamm; C T Speakman; Y H Chye; M M Henry
Related Documents :
679079 - Oropharyngeal dysphagia in patients with oculopharyngeal muscular dystrophy.
22953879 - Effect of high hydrostatic pressure on antimicrobial activity and quality of manuka honey.
8181409 - Transanal ultrasound and manometry in the evaluation of fecal incontinence.
1151679 - Technique for assessment of local effects of substances found in bile upon opening pres...
1278649 - Studies on the mechanism of esophagitis-induced lower esophageal sphincter hypotension ...
23162229 - Improved wound management by regulated negative pressure-assisted wound therapy and reg...
9397489 - Effects of adrenergic and muscarinic agonist stimulation on ip3 and cyclic nucleotide l...
12821259 - Left ventricular structural and functional characteristics in cushing's syndrome.
3860879 - Antihypertensive activity and metabolic rate of prostaglandin e1 in surgical patients u...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  81     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-02-23     Completed Date:  1995-02-23     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1689-92     Citation Subset:  AIM; IM    
Affiliation:
Department of Gastroenterology, Central Middlesex Hospital, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Anal Canal / physiology
Female
Humans
Male
Middle Aged
Muscle Contraction
Parity*
Pressure
Prospective Studies
Reaction Time
Rectum / physiology*
Sensation
Sex Characteristics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Motor abnormalities in the terminal ileum of patients with chronic idiopathic constipation.
Next Document:  Virtual reality and laparoscopic surgery.