Document Detail

Effect of age, sex and parity on anorectal function.
MedLine Citation:
PMID:  7827909     Owner:  NLM     Status:  MEDLINE    
Ninety-one healthy subjects (51 women; age range 16-85 years) were studied prospectively to determine the effect of age, sex and parity on anorectal function. Maximum resting pressure, voluntary contraction pressure, rectal sensation to distension, rectal and mid-anal electrosensitivity, perineal descent, pudendal nerve terminal motor latency and fibre density of the external and sphincter were measured. Sex influenced mean(s.d.) voluntary contraction pressure (148(56) versus 95(43) cmH2O for men versus women, P < 0.0001), perineal descent on straining (1.0(0.5) versus 1.3(0.4) cm, P = 0.02) and fibre density (1.43(0.14) versus 1.52(0.15), P = 0.02). Age influenced resting pressure (r = -0.43, P = 0.0001), perineal position at rest (r = -0.55, P < or = 0.0001), mid-anal electrosensitivity (r = 0.42, P = 0.0001) and rectal electrosensitivity (r = 0.54, P < 0.0001). Parity affected mean(s.d.) voluntary contraction pressure (105(53) versus 75(20) cmH2O for nulliparous versus parous women, P = 0.04) and mid-anal electrosensitivity (5.3(2.3) versus 4.5(2.3) mA, P = 0.02). Increasing age leads to perineal descent at rest, slowed pudendal nerve conduction, a fall in resting anal pressure and decreased anorectal sensory function. Women have a lower and squeeze pressure, greater perineal descent, longer pudendal nerve terminal motor latency and a greater muscle fibre density than men. Parity leads only to lower squeeze pressure.
J S Jameson; Y W Chia; M A Kamm; C T Speakman; Y H Chye; M M Henry
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  81     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-02-23     Completed Date:  1995-02-23     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1689-92     Citation Subset:  AIM; IM    
Department of Gastroenterology, Central Middlesex Hospital, London, UK.
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MeSH Terms
Age Factors
Aged, 80 and over
Anal Canal / physiology
Middle Aged
Muscle Contraction
Prospective Studies
Reaction Time
Rectum / physiology*
Sex Characteristics*

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