Document Detail

Effect of age and preoperative airway obstruction on lung function after coronary artery bypass grafting.
MedLine Citation:
PMID:  8328838     Owner:  NLM     Status:  MEDLINE    
To determine whether age or obstructive lung disease affects pulmonary function changes caused by uncomplicated coronary artery bypass grafting, we measured pulmonary function before operation and then 3 or 4 days, 7 days, and 17 +/- 2.2 weeks after operation in elderly patients (age, 74.8 +/- 3.3 years) and patients with obstructive lung disease (ratio of forced expiratory volume in 1 second to forced vital capacity, 0.60 +/- 8.8) and compared the results with those of a "normal" group. In all three groups a severe restrictive defect developed on day 3 (vital capacity, 61% +/- 20% of the preoperative value). Vital capacity recovered to 76.4% +/- 18.5% of the preoperative value on day 7. Three months after coronary artery bypass grafting, lung function had recovered to preoperative baseline (p > 0.2). The percent change from baseline in vital capacity, forced expiratory volume in 1 second, total lung capacity, and diffusing capacity for carbon monoxide was the same in all three groups throughout the study. A severe, reversible restrictive pulmonary function change follows coronary artery bypass grafting. This change is not affected by age or preexisting moderately severe obstructive lung disease.
G W Wahl; A J Swinburne; A J Fedullo; D K Lee; D Shayne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  56     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1993 Jul 
Date Detail:
Created Date:  1993-08-12     Completed Date:  1993-08-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  104-7     Citation Subset:  AIM; IM    
Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester General Hospital, New York 14621.
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MeSH Terms
Age Factors
Coronary Artery Bypass*
Coronary Disease / complications
Lung Diseases, Obstructive / complications,  physiopathology*
Middle Aged
Postoperative Complications
Respiratory Mechanics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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