Document Detail

Effect of chlorhexidine/EDTA/Tris against bacterial isolates from clinical specimens.
MedLine Citation:
PMID:  3116368     Owner:  NLM     Status:  MEDLINE    
Chlorhexidine/EDTA/Tris was more active compared with chlorhexidine against the following species of organisms: Acinetobacter species, Citrobacter species, Enterobacter species, Escherichia coli, Proteus mirabilis, Providence species, Pseudomonas species, Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus faecalis, when tested in isosensitest agar. The addition of 20% serum to the medium reduced its effectiveness mainly against Providence species, Proteus species, and Streptococcus faecalis. However, the potential for this solution as a bladder instillation or topical antiseptic should be considered because of its reduced side effects compared with chlorhexidine alone, and its increased general effectiveness against all isolates tested.
W E Harper; J A Epis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Microbios     Volume:  51     ISSN:  0026-2633     ISO Abbreviation:  Microbios     Publication Date:  1987  
Date Detail:
Created Date:  1987-11-09     Completed Date:  1987-11-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207257     Medline TA:  Microbios     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  107-12     Citation Subset:  IM    
Department of Microbiology, Royal Perth Hospital, Western Australia.
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MeSH Terms
Bacteria / drug effects*,  growth & development,  isolation & purification
Chlorhexidine / pharmacology*
Drug Combinations
Edetic Acid / pharmacology*
Tromethamine / pharmacology*
Wound Infection / microbiology
Reg. No./Substance:
0/Drug Combinations; 55-56-1/Chlorhexidine; 60-00-4/Edetic Acid; 77-86-1/Tromethamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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