| Effect of adipic dihydrazide modification on the performance of collagen/hyaluronic acid scaffold. | |
| | |
MedLine Citation:
|
PMID: 19810117 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Collagen and hydrazide-functionalized hyaluronic acid derivatives were hybridized by gelating and genipin crosslinking to form composite hydrogel. The study contributed to the understanding of the effects of adipic dihydrazide modification on the physicochemical and biological properties of the collagen/hyaluronic acid scaffold. The investigation included morphology observation, mechanical measurement, swelling evaluation, and collagenase degradation. The results revealed that the stability of composites was increased through adipic dihydrazide modification and genipin crosslinking. The improved biocompatibility and retention of hyaluronic acid made the composite material more favorable to chondrocytes growing, suggesting the prepared scaffold might be high potential for chondrogenesis. |
| | |
Authors:
|
Ling Zhang; Yumei Xiao; Bo Jiang; Hongsong Fan; Xingdong Zhang |
Related Documents
:
|
6819817 - A method for the hyaluronic acid synthetase assay in human skin. 22551417 - Physcomitrella patens activates reinforcement of the cell wall, programmed cell death a... 22526807 - Asymmetric bioreduction of activated alkenes by a novel isolate of achromobacter specie... 19302997 - Serum mesothelin has a higher diagnostic utility than hyaluronic acid in malignant meso... 240807 - Soluble macromolecular complexes involving bacterial teichoic acids. 482977 - Treatment of metabolic alkalosis with intravenous hydrochloric acid. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of biomedical materials research. Part B, Applied biomaterials Volume: 92 ISSN: 1552-4981 ISO Abbreviation: J. Biomed. Mater. Res. Part B Appl. Biomater. Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-01-28 Completed Date: 2010-04-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101234238 Medline TA: J Biomed Mater Res B Appl Biomater Country: United States |
Other Details:
|
Languages: eng Pagination: 307-16 Citation Subset: IM |
Affiliation:
|
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Absorbable Implants Adipic Acids / chemistry* Cell Adhesion Cell Proliferation Chondrocytes / physiology Collagen Type I / chemistry* Cross-Linking Reagents Enzymes / chemistry Humans Hyaluronic Acid / chemistry* Immunohistochemistry Iridoids / chemistry Materials Testing Microscopy, Electron, Scanning Porosity Spectrophotometry, Infrared Spectroscopy, Fourier Transform Infrared Stress, Mechanical Tensile Strength Tissue Scaffolds / chemistry* Water / chemistry |
| Chemical | |
Reg. No./Substance:
|
0/Adipic Acids; 0/Collagen Type I; 0/Cross-Linking Reagents; 0/Enzymes; 0/Iridoids; 1071-93-8/adipic dihydrazide; 6902-77-8/genipin; 7732-18-5/Water; 9004-61-9/Hyaluronic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Corono-apical leakage of various root filling materials using two different penetration models-A 3-m...
Next Document: Dental glass-reinforced composite for caries inhibition: calcium phosphate ion release and mechanica...