Document Detail

Effect of acute plasma volume expansion on thermoregulation and exercise performance in the heat.
MedLine Citation:
PMID:  10795787     Owner:  NLM     Status:  MEDLINE    
PURPOSE: We investigated the effects of acute plasma volume expansion on exercise performance in the heat. METHODS: Six moderately trained men cycled for 40 min at 64 +/- 2% peak pulmonary oxygen uptake (VO2peak) followed by an individual performance time trial, where subjects completed a set amount of work (267 +/- 15 kJ) in as little time as possible. Exercise trials were performed at 35 degrees C with a relative humidity of 40%. Subjects performed two exercise trials: one after 13.1 +/- 1% acute plasma volume expansion (PVE), which was achieved by the intravenous infusion of 8 mL x kg(-1) body weight of Hemaccel (35 g x L(-1) polygeline, 145 mmol x L(-1) Na+, and 145 mmol x L(-1) Cl-) and the other without prior treatment (CON). RESULTS: Core temperature, skin blood flow, and heart rate progressively increased (P < 0.05) during exercise, but no differences were observed between trials. Plasma glucose and lactate were similar at rest and during exercise, as was VO2 during exercise. Exercise performance was not influenced by plasma volume expansion (CON 17.5 +/- 0.4 min and PVE 17.1 +/- 0.2 min). CONCLUSION: These data suggest that, in moderately trained men, plasma volume expansion alone does not enhance thermoregulatory function and exercise performance during moderate intensity exercise in the heat.
M J Watt; A P Garnham; M A Febbraio; M Hargreaves
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  32     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-06-19     Completed Date:  2000-06-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  958-62     Citation Subset:  IM; S    
School of Health Sciences, Deakin University, Burwood, Australia.
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MeSH Terms
Acclimatization / physiology
Bicycling / physiology
Blood Glucose / metabolism
Body Temperature Regulation / physiology*
Exercise / physiology*
Heart Rate / physiology
Hot Temperature* / adverse effects
Lactic Acid / blood
Plasma Volume / physiology*
Reg. No./Substance:
0/Blood Glucose; 50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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