| Effect of acute hypoxia on lung fluid balance in the prerecruited dog lung. | |
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MedLine Citation:
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PMID: 3768567 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lung lymph flow and protein transport were measured in eight anaesthetized dogs while acute hypoxic exposure (FIO2 = 0.10) was performed on prerecruited lung (achieved by an increased left atrial pressure). It was found that the lung lymph flow increase observed during hypoxia (from 71.8 +/- 47.5 to 100.8 +/- 78.4 microliters X min-1; p less than 0.05) was associated to an unchanged lymph/plasma protein concentration ratio (from 0.60 +/- 0.9 to 0.60 +/- 0.11). During recovery from hypoxia, lymph flow remained at a higher level than before hypoxia (respectively 87.8 +/- 49.5 and 71.8 +/- 47.5 microliters X min-1). These results suggest that the mild hypoxia-induced oedema is rather a high permeability oedema than an haemodynamic oedema. A graphic representation of protein clearance changes versus lymph flow changes was used in order to discriminate between high permeability and haemodynamic oedemas at their early stage. |
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Authors:
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D J Martin; P Baconnier; G Benchetrit; F Royer; F A Grimbert |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bulletin européen de physiopathologie respiratoire Volume: 22 ISSN: 0395-3890 ISO Abbreviation: Bull Eur Physiopathol Respir Publication Date: 1986 Jul-Aug |
Date Detail:
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Created Date: 1986-12-02 Completed Date: 1986-12-02 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7605263 Medline TA: Bull Eur Physiopathol Respir Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 335-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anoxia / metabolism, physiopathology* Blood Proteins / metabolism* Capillary Permeability Dogs Hemodynamics Lung / metabolism Lymph / metabolism* Myocardial Contraction Pulmonary Edema / metabolism, physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Blood Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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