| Effect of abruptly increased intrathoracic pressure on coronary blood flow velocity in patients. | |
| | |
MedLine Citation:
|
PMID: 2181839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To assess the effects of abruptly increased intrathoracic pressure on coronary blood flow, arterial pressure, heart rate, and intracoronary Doppler blood flow velocity were measured continuously during cough(s) and again during the four phases of the Valsalva maneuver in 14 patients. Coughing significantly increased the systolic pressure (137 +/- 25 to 176 +/- 30 mm Hg), diastolic pressure (72 +/- 10 to 84 +/- 18 mm Hg), and arterial pulse pressure (65 +/- 27 to 92 +/- 35 mm Hg), with no change in heart rate. The mean coronary flow velocity decreased (17 +/- 10 to 14 +/- 12 cm/sec, p less than 0.03). During the Valsalva maneuver, despite marked reduction in the mean arterial pressure during phase III (96 +/- 12 to 68 +/- 14 mm Hg, p less than 0.05), the reduction of coronary blood flow velocity did not achieve statistical significance. These data demonstrate that neither type of abrupt physiologic increase in intrathoracic pressure enhances coronary blood flow. Coughing does not improve coronary perfusion pressures or flow velocity, despite marked increases in arterial diastolic pressure. The Valsalva maneuver, for the most part, does not significantly alter coronary blood flow velocity. |
| | |
Authors:
|
M J Kern; C Gudipati; S Tatineni; F Aguirre; H Serota; U Deligonul |
Related Documents
:
|
9085349 - Role of nitric oxide (no) in the regulation of coronary circulation. 7060229 - The effects of the coronary capacitance on the interpretation of diastolic pressure-flo... 1713989 - An alpha-adrenergic coronary constriction during esophageal distention in the dog. 12219879 - Inflection point of ascending aortic waveform is a powerful predictor of restenosis aft... 1132069 - Inhibition of coronary blood flow by a vascular waterfall mechanism. 8821549 - Cocaine-induced microvascular vasoconstriction but differential systemic haemodynamic r... 7258769 - Systemic and digital vascular effects of intravenous histamine in the pony. 498589 - Hepatic microvascular effects of terbutaline in experimental cardiogenic shock in rats. 3249269 - Effect of heart rate on the end-systolic wall stress-mean velocity of circumferential f... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American heart journal Volume: 119 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1990 Apr |
Date Detail:
|
Created Date: 1990-05-04 Completed Date: 1990-05-04 Revised Date: 2006-02-27 |
Medline Journal Info:
|
Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 863-70 Citation Subset: AIM; IM |
Affiliation:
|
Cardiology Division, St. Louis University Hospital, MO 63110. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Flow Velocity
/
physiology Blood Pressure / physiology Coronary Circulation / physiology* Coronary Vessels / physiology Cough / physiopathology* Female Heart Rate / physiology Humans Male Middle Aged Pressure Thorax / physiology Ultrasonics Ultrasonography Valsalva Maneuver / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Management of ectopic pregnancy.
Next Document: Selecting therapy for sustained ventricular tachycardias: importance of the sensitivity and specific...