| Effect of Zajdela ascites hepatoma on the activity and synthesis of liver histidase of tumor-bearing rats. | |
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MedLine Citation:
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PMID: 6744236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The synthesis of histidase occurs only in free polyribosomes. The relative content of histidase synthesizing polyribosomes in rat liver, in Zajdela ascites hepatoma cells and in the liver of tumor-bearing rats is equal to 1.35%, 0.11% and 0.57%, respectively (of the total amount of free polyribosomes). It was found that hepatoma cell sap has an inhibitory effect on the synthesis of proteins in the cell-free system reconstructed from polyribosomes and cell sap of control rats. |
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Authors:
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S A Fedorov; P Z Khasigov; Nocolaev AYa |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Cancer letters Volume: 23 ISSN: 0304-3835 ISO Abbreviation: Cancer Lett. Publication Date: 1984 May |
Date Detail:
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Created Date: 1984-08-24 Completed Date: 1984-08-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600053 Medline TA: Cancer Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 67-71 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ammonia-Lyases
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biosynthesis* Animals Brain / metabolism Cell Fractionation Cell Line Histidine Ammonia-Lyase / antagonists & inhibitors, biosynthesis* Liver / enzymology* Liver Neoplasms, Experimental / metabolism* Male Neoplasm Transplantation Polyribosomes / metabolism* Rats Rats, Inbred Strains Tissue Extracts / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Tissue Extracts; EC 4.3.1.-/Ammonia-Lyases; EC 4.3.1.3/Histidine Ammonia-Lyase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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