| Effect of Yinian Jiangya Yin on primary hypertension in early stage--a clinical observation on 40 patients. | |
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MedLine Citation:
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PMID: 21053621 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To observe the effect of Yinian Jiangya Yin (Decoction for lowering blood pressure to prolong life) on patients with early hypertension and its mechanism on the function of vascular endotheliocytes. METHODS: The 79 patients with early primary hypertension belonging to the TCM syndrome of stagnation of phlegm and blood stasis in meridians and hyperactivity of the liver-yang were randomly divided into a treatment group of 40 patients treated with Yinian Jiangya Yin and a control group of 39 patients treated with Tianma Gouteng Yin (Decoction of Gastrodia and Uncaria). The changes in score of TCM syndrome and in blood pressure before and after treatment were observed in the two groups. The contents of nitrogen monoxide (NO) and endothelin (ET) in serum after treatment were determined. RESULTS: There was a statistical difference (P < 0.05) in score of TCM syndrome, effect of lowering blood pressure, and the contents of ET and NO in serum after treatment between the two groups. CONCLUSION: The effect of Yinian Jiangya Yin on improving TCM syndrome of patients with primary hypertension in early stage and on lowering blood pressure may be related to its regulating the imbalanced condition between ET and NO for restoring the function of endothelium-dependent vasodilation. |
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Authors:
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Yong-Hua Zhao; Yu-De Liu; Ying Guan; Nai-Wei Liu |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine Volume: 30 ISSN: 0255-2922 ISO Abbreviation: J Tradit Chin Med Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-11-08 Completed Date: 2010-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211546 Medline TA: J Tradit Chin Med Country: China |
Other Details:
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Languages: eng Pagination: 171-5 Citation Subset: IM |
Affiliation:
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TCM College, Macao University of Science and Technology, Macao, China. yhzhao@must.edu.mo |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure
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drug effects Drugs, Chinese Herbal / therapeutic use* Endothelins / blood Female Humans Hypertension / blood, diagnosis, drug therapy*, physiopathology Male Middle Aged Nitric Oxide / blood Yin Deficiency / blood, diagnosis, drug therapy*, physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Drugs, Chinese Herbal; 0/Endothelins; 10102-43-9/Nitric Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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