Document Detail

The Effect of Weight Loss on the Cardiac Structure and Function After Laparoscopic Adjustable Gastric Banding Surgery in Morbidly Obese Individuals.
MedLine Citation:
PMID:  24866689     Owner:  NLM     Status:  Publisher    
BACKGROUND: Herein, we investigate the anthropometric, biochemical and left ventricle (LV) geometry changes following the laparoscopic adjustable gastric banding (LAGB) operation in morbidly obese individuals.
METHODS: Eighty-three morbidly obese participants (mean age, 46.1 ± 11.5 years; 30.1 % men), scheduled for elective LAGB were examined before and 12 months after the surgery. LV geometry and diastolic function were investigated by 2-dimensional echocardiography, whereas laboratory tests assessed the glycaemic, serum lipid and inflammatory marker profiles.
RESULTS: Twelve months after the operation, body mass index (BMI) decreased from 46.9 ± 7.2 kg/m(2) to 40.1 ± 8.2 kg/m(2) (p < 0.05), which was associated with the significant improvements in glycaemic control, inflammatory state, LV end-diastolic diameter (53.6 ± 4.6 mm vs. 52.9 ± 4.1 mm, p < 0.05), LV mass (223.6 ± 61.3 vs. 215.4 ± 52.7 g, p < 0.05) and LV mass index (53.9 ± 14.1 g/m(2.7) vs. 52.0 ± 12.3 g/m(2.7), p < 0.05). However, no overall improvements in LV geometry or the prevalence of LV hypertrophy subtypes were recorded 12 months after the LAGB. The reduction in LV end-diastolic diameter (ß = 0.56, p = 0.0001) and BMI (ß = 0.26, p = 0.015) were both associated with diminished LV mass. Additionally, a statistically significant correlation between LV mass and changes in BMI (R = 0.29, p = 0.007), waist circumference (R = 0.32, p = 0.004), LV end-diastolic diameter (R = 0.63, p = 0.0001) and E-wave deceleration time (R = -0.24, p = 0.03) were observed within our study population.
CONCLUSIONS: LV mass decreases 12 months after LAGB surgery, but no improvements in LV geometry and function occur. The regression of LV mass is better predicted by weight loss than by reduction in blood pressure or changes in metabolic parameters.
Vilma Dzenkeviciūte; Zaneta Petrulioniene; Virginijus Sapoka; Sigita Aidietiene; Lina Abaraviciute
Related Documents :
1778679 - The effects of long-term hypoxia on epicardium and myocardium in developing chick embry...
6478549 - Interaction between hemorrhagic hypotension and hypoxia in regulation of renal vascular...
24866689 - The effect of weight loss on the cardiac structure and function after laparoscopic adju...
6508019 - Hypoxia-altitude simulation test. evaluation of patients with chronic airway obstruction.
6419 - Circulatory effects of prolonged hypoxia before and during antihistamine.
2038069 - Dual role of hypoxanthine in the reoxygenation of hypoxic isolated rat hearts.
9651969 - Gosling's doppler pulsatility index revisited.
1854569 - Aging, autonomic function, and the perception of angina.
11078349 - Gender differences in hemodynamic responses to endothelin-1.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-28
Journal Detail:
Title:  Obesity surgery     Volume:  -     ISSN:  1708-0428     ISO Abbreviation:  Obes Surg     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9106714     Medline TA:  Obes Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Measuring malnutrition.
Next Document:  Magnetoresponsive Discoidal Photonic Crystals Toward Active Color Pigments.