| The effect of water disinfection by-products on pregnancy outcomes in two southeastern US communities. | |
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MedLine Citation:
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PMID: 21915074 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine if exposure to disinfection by-products (DBPs) during gestation increases the risk of adverse birth outcomes, specifically term small for gestational age (SGA) birth, preterm birth (PTB), and very PTB (<32 weeks' gestation). METHODS: We used weekly measurements total trihalomethanes (TTHMs), five haloacetic acids (HAA5), and total organic halides (TOX) collected from two distribution systems to evaluate the associations between DBP concentrations and term SGA, PTB, and very PTB using logistic regression. RESULTS: We found no associations between DBPs and term-SGA. In the site with higher concentrations of bromine-containing DBPs, we found an association between TOX and PTB; this association was larger, though less precise, for very PTB. CONCLUSIONS: Our results do not support an association between TTHMs or HAA5 and the birth outcomes investigated, but an association was found between increased TOX and PTB. |
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Authors:
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Bethany Jablonski Horton; Thomas J Luben; Amy H Herring; David A Savitz; Philip C Singer; Howard S Weinberg; Katherine E Hartmann |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine Volume: 53 ISSN: 1536-5948 ISO Abbreviation: J. Occup. Environ. Med. Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-10 Completed Date: 2012-02-22 Revised Date: 2013-02-15 |
Medline Journal Info:
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Nlm Unique ID: 9504688 Medline TA: J Occup Environ Med Country: United States |
Other Details:
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Languages: eng Pagination: 1172-8 Citation Subset: IM |
Affiliation:
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Departments of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA. bethjab@email.unc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Weight* Female Fetal Growth Retardation / epidemiology* Gestational Age Humans Hydrocarbons, Brominated / adverse effects, analysis* Hydrocarbons, Chlorinated / adverse effects, analysis* Infant, Newborn Logistic Models Odds Ratio Pregnancy Pregnancy Outcome Premature Birth / epidemiology* Southeastern United States Trihalomethanes / adverse effects, analysis Water Purification* Water Supply / analysis Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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P30E510126//PHS HHS; R24 HD050924/HD/NICHD NIH HHS; T32 ES007018/ES/NIEHS NIH HHS; T32ES007018/ES/NIEHS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Hydrocarbons, Brominated; 0/Hydrocarbons, Chlorinated; 0/Trihalomethanes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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