Document Detail


Effect of UVA or UVB irradiation on cutaneous lipids in films or in solution.
MedLine Citation:
PMID:  20132514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The barrier function of the skin is largely due to the stratum corneum which is essentially composed of lipids. Different external factors, such as UV irradiation, affect this skin layer and are responsible for a destabilization of the supramolecular organization of its constituted lipids. In this work, mass spectrometry and infrared spectroscopy are combined to study the correlation between the formation of oxidative compounds by UV irradiation and the lipid organization. Experiments were carried out on unsaturated lipids in film or solution form, exposed to UVA or UVB irradiation. UV exposure leads to the formation of oxygenated entities in the case of lipids with an unsaturated fatty acid moiety, resulting in a decrease in their packing which is greater when the lipids are in solution. The packing decrease is even greater following UVB irradiation.
Authors:
Chloé Merle; Cécile Laugel; Arlette Baillet-Guffroy
Related Documents :
21394224 - Structural, chemical and electrochemical characterization of poly(3,4-ethylenedioxythio...
15985374 - Iron salts in solid state and in frozen solutions as dosimeters for low irradiation tem...
17973054 - Prebiotic chemistry: chemical evolution of organics on the primitive earth under simula...
21552644 - Continuous synthesis of monodispersed silver nanoparticles using a homogeneous heating ...
12800144 - Interfacial versus homogeneous enzymatic cleavage of mandelonitrile by hydroxynitrile l...
8095744 - Transepidermal water loss and water content in the stratum corneum in infantile seborrh...
Publication Detail:
Type:  Journal Article     Date:  2010-01-27
Journal Detail:
Title:  Photochemistry and photobiology     Volume:  86     ISSN:  1751-1097     ISO Abbreviation:  Photochem. Photobiol.     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-06-16     Completed Date:  2010-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376425     Medline TA:  Photochem Photobiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  553-62     Citation Subset:  IM    
Affiliation:
Group Chimie Analytique de Paris-Sud EA 4041, IFR 141 School of Pharmacy, Univ. Paris-Sud F, Châtenay-Malabry, France. chloe.merle@club-internet.fr
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Fatty Acids, Unsaturated / radiation effects*
Lipids / radiation effects*
Mass Spectrometry
Models, Biological
Oxidation-Reduction
Skin / chemistry*
Solutions
Spectroscopy, Fourier Transform Infrared
Ultraviolet Rays / adverse effects*
Chemical
Reg. No./Substance:
0/Fatty Acids, Unsaturated; 0/Lipids; 0/Solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cellular Uptake and Photodynamic Activity of Protein Nanocages Containing Methylene Blue Photosensit...
Next Document:  Production of antibodies in plants: status after twenty years.