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Effect of UV Light on RNA-Directed DNA Polymerase Activity of Murine Oncornaviruses.
MedLine Citation:
PMID:  16789159     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The UV inactivation of RNA-directed DNA polymerase activity of Rauscher leukemia virus was shown to be due to damage to the protein. The UV dose resulting in 37% survival of viral polymerase activity at 254 nm was 2.4 x 10(4) to 3.1 x 10(4) ergs/mm(2). The inactivation rate of p30, a major internal viral protein, was much slower.
Authors:
G G Lovinger; H P Ling; R V Gilden; M Hatanaka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of virology     Volume:  15     ISSN:  0022-538X     ISO Abbreviation:  J. Virol.     Publication Date:  1975 May 
Date Detail:
Created Date:  2010-06-29     Completed Date:  2010-06-29     Revised Date:  2010-09-14    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1273-5     Citation Subset:  -    
Affiliation:
Flow Laboratories, Inc., Rockville, Maryland 20852.
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