| Effect of sodium fluoride, ampicillin, and chlorhexidine on Streptococcus mutans biofilm detachment. | |
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MedLine Citation:
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PMID: 22664966 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We examined the effect of three clinically used antimicrobials on Streptococcus mutans UA159 biofilm detachment under flow conditions. Sodium fluoride (NaF) and chlorhexidine at MIC levels promoted biofilm detachment and inhibited detachment when concentrations were higher than the MIC and reduced detached-cell viability only at high concentrations. Ampicillin at all concentrations tested inhibited detachment and reduced the percentage of viable biofilm-detached cells. All the three antimicrobial treatments reduced biofilm live/dead cell ratios. |
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Authors:
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Jia Liu; Jun-Qi Ling; Kai Zhang; Li-Jun Huo; Yang Ning |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2012-06-04 |
Journal Detail:
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Title: Antimicrobial agents and chemotherapy Volume: 56 ISSN: 1098-6596 ISO Abbreviation: Antimicrob. Agents Chemother. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-07-24 Completed Date: 2013-02-12 Revised Date: 2013-04-08 |
Medline Journal Info:
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Nlm Unique ID: 0315061 Medline TA: Antimicrob Agents Chemother Country: United States |
Other Details:
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Languages: eng Pagination: 4532-5 Citation Subset: IM |
Affiliation:
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Institute of Stomatological Research, Guanghua School of Stomotology, Sun Yat-sen University, Guangzhou, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ampicillin
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pharmacology* Anti-Bacterial Agents / pharmacology Anti-Infective Agents, Local / pharmacology Biofilms / drug effects* Cariostatic Agents / pharmacology Chlorhexidine / pharmacology* Microbial Sensitivity Tests Sodium Fluoride / pharmacology* Streptococcus mutans / drug effects*, physiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Infective Agents, Local; 0/Cariostatic Agents; 55-56-1/Chlorhexidine; 69-53-4/Ampicillin; 7681-49-4/Sodium Fluoride |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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