Document Detail

Effect of Side-Stream Smoking on Random-Pattern Skin Flap Survival in Rats.
MedLine Citation:
PMID:  24322641     Owner:  NLM     Status:  Publisher    
The secondhand exposure to cigarette smoke is being considered evil, and damage caused by this passive exposure has been proven by several studies. To investigate the effects of sidestream smoke exposure on random-pattern skin flap survival, 20 female rats were separated into 2 groups: group A (n = 10) was exposed 6 weeks to the smoke from the burning cigarette (passive smoking) and group B (n = 10) was the control group. After 6 weeks of exposition, a dorsal McFarlane flap of 4 × 10 cm was performed in all rats. Two weeks after this procedure, the ratio of necrotic and total areas was calculated using computer programs. The median area of necrosis in group A was 29.5%, significantly higher than that in group B with 17.5% (P < 0.024). In conclusion, this study suggests increased risk of random-pattern skin flap necrosis after sidestream exposure to cigarette smoke.
Anajara Gazzalle; Lourenço Frigeri Teixeira; Alice Cardoso Pellizzari; Fernanda Cocolichio; Juliana Tonietto Zampieri; Daniel Rauber; Luíse S Pezzin; Vanessa D Zago; Jefferson Luis Braga-Silva
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-7-11
Journal Detail:
Title:  Annals of plastic surgery     Volume:  -     ISSN:  1536-3708     ISO Abbreviation:  Ann Plast Surg     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7805336     Medline TA:  Ann Plast Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
From the *Division of Hand Surgery and Reconstructive Microsurgery, Hospital São Lucas, and †School of Medicine at the Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
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