Document Detail

The Effect of Retrograde Autologous Priming of the Cardiopulmonary Bypass Circuit on Cerebral Oxygenation.
MedLine Citation:
PMID:  21576024     Owner:  NLM     Status:  Publisher    
OBJECTIVE:: The aim of this study was to investigate the effect of retrograde autologous priming (RAP) of the cardiopulmonary bypass (CPB) circuit on cerebral oxygenation. DESIGN:: A retrospective cohort study. SETTING:: A university hospital. PARTICIPANTS:: Ninety-four patients undergoing CPB. INTERVENTIONS:: CPB was primed with a RAP technique in the RAP group (n = 46) or with a conventional technique in the control group (n = 48). MEASUREMENT AND MAIN RESULTS:: Cerebral oxygenation was monitored by measuring the regional cerebral oxygen saturation (rSO(2)). The rSO(2) and Hct values were compared between the groups during surgery. During the CPB period, the RAP group showed significantly higher values for rSO(2) (%) (immediately after the onset of CPB: 51.3 ± 8.4 and 56.3 ± 8.3; 30 minutes after the onset of CPB: 56.3 ± 5.1 and 59.7 ± 7.0; control group and RAP groups, respectively; p < 0.01 for each) and Hct (%) (immediately after the onset of CPB: 21.1 ± 3.7 and 23.1 ± 3.3; 30 minutes after the onset of CPB: 21.9 ± 3.7 and 23.3 ± 2.3; control group and RAP group, respectively; p < 0.02 for each). However, the 2 groups did not differ in rSO(2) (%) (67.2 ± 6.3 and 67.8 ± 6.4) or Hct (%) (27.8 ± 4.1 and 28.9 ± 3.6, control group and RAP group, respectively) at the end of the surgery. CONCLUSIONS:: The application of RAP to CPB limits the degree of hemodilution and improves cerebral oxygenation during CPB. The present findings suggest a potential benefit of RAP from a neurologic aspect.
Jinyoung Hwang; Jin Huh; Jinhee Kim; Sanghyon Park; Jeongwon Hwang; Francis Sahngun Nahm; Sunghee Hahn
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-14
Journal Detail:
Title:  Journal of cardiothoracic and vascular anesthesia     Volume:  -     ISSN:  1532-8422     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110208     Medline TA:  J Cardiothorac Vasc Anesth     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Kyonggido, Korea.
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